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In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T cells.
Christ A, Maas SL, Jin H, Lu C, Legein B, Wijnands E, Temmerman L, Otten J, Isaacs A, Zenke M, Stoll M, Biessen EAL, van der Vorst EPC. Christ A, et al. Among authors: wijnands e. Free Radic Biol Med. 2024 Jan;210:406-415. doi: 10.1016/j.freeradbiomed.2023.11.044. Epub 2023 Dec 5. Free Radic Biol Med. 2024. PMID: 38061606 Free article.
Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair.
Fontaine MAC, Jin H, Gagliardi M, Rousch M, Wijnands E, Stoll M, Li X, Schurgers L, Reutelingsperger C, Schalkwijk C, van den Akker NMS, Molin DGM, Gullestad L, Eritsland J, Hoffman P, Skjelland M, Andersen GØ, Aukrust P, Karel J, Smirnov E, Halvorsen B, Temmerman L, Biessen EAL. Fontaine MAC, et al. Among authors: wijnands e. Adv Sci (Weinh). 2023 Feb;10(5):e2203053. doi: 10.1002/advs.202203053. Epub 2022 Dec 16. Adv Sci (Weinh). 2023. PMID: 36526599 Free PMC article.
Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context.
Goossens P, Lu C, Cao J, Gijbels MJ, Karel JMH, Wijnands E, Claes BSR, Fazzi GE, Hendriks TFE, Wouters K, Smirnov E, van Zandvoort MJM, Balluff B, Cuypers E, Donners MMPC, Heeren RMA, Biessen EAL. Goossens P, et al. Among authors: wijnands e. Cell Metab. 2022 Aug 2;34(8):1214-1225.e6. doi: 10.1016/j.cmet.2022.06.012. Epub 2022 Jul 19. Cell Metab. 2022. PMID: 35858629 Free article.
FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4.
Crivelli SM, Luo Q, Kruining DV, Giovagnoni C, Mané-Damas M, den Hoedt S, Berkes D, De Vries HE, Mulder MT, Walter J, Waelkens E, Derua R, Swinnen JV, Dehairs J, Wijnands EPM, Bieberich E, Losen M, Martinez-Martinez P. Crivelli SM, et al. Among authors: wijnands epm. Biomed Pharmacother. 2022 Aug;152:113240. doi: 10.1016/j.biopha.2022.113240. Epub 2022 Jun 9. Biomed Pharmacother. 2022. PMID: 35689862 Free article.
Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis.
Carai P, Papageorgiou AP, Van Linthout S, Deckx S, Velthuis S, Lutgens E, Wijnands E, Tschöpe C, Schmuttermaier C, Kzhyshkowska J, Jones EAV, Heymans S. Carai P, et al. Among authors: wijnands e. J Mol Cell Cardiol. 2022 Apr;165:31-39. doi: 10.1016/j.yjmcc.2021.12.009. Epub 2021 Dec 28. J Mol Cell Cardiol. 2022. PMID: 34968453 Free article.
CCR6 Deficiency Increases Infarct Size after Murine Acute Myocardial Infarction.
Schumacher D, Liehn EA, Singh A, Curaj A, Wijnands E, Lira SA, Tacke F, Jankowski J, Biessen EAL, van der Vorst EPC. Schumacher D, et al. Among authors: wijnands e. Biomedicines. 2021 Oct 25;9(11):1532. doi: 10.3390/biomedicines9111532. Biomedicines. 2021. PMID: 34829761 Free PMC article.
Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension.
Kerkhofs D, van Hagen BT, Milanova IV, Schell KJ, van Essen H, Wijnands E, Goossens P, Blankesteijn WM, Unger T, Prickaerts J, Biessen EA, van Oostenbrugge RJ, Foulquier S. Kerkhofs D, et al. Among authors: wijnands e. Theranostics. 2020 Jul 25;10(21):9512-9527. doi: 10.7150/thno.44394. eCollection 2020. Theranostics. 2020. PMID: 32863942 Free PMC article.
Author Correction: Ablation of CD8α+ dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice.
Legein B, Janssen EM, Theelen TL, Gijbels MJ, Walraven J, Klarquist JS, Hennies CM, Wouters K, Seijkens TTP, Wijnands E, Sluimer JC, Lutgens E, Zenke M, Hildner K, Biessen EAL, Temmerman L. Legein B, et al. Among authors: wijnands e. Sci Rep. 2020 May 26;10(1):8747. doi: 10.1038/s41598-020-65653-2. Sci Rep. 2020. PMID: 32457341 Free PMC article.
40 results