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Extracellular targeted protein degradation: an emerging modality for drug discovery.
Nat Rev Drug Discov. 2024 Feb;23(2):126-140. doi: 10.1038/s41573-023-00833-z. Epub 2023 Dec 7.
Nat Rev Drug Discov. 2024.
PMID: 38062152
Review.
Insights into modular polyketide synthase loops aided by repetitive sequences.
Hirsch M, Kumru K, Desai RR, Fitzgerald BJ, Miyazawa T, Ray KA, Saif N, Spears S, Keatinge-Clay AT.
Hirsch M, et al. Among authors: kumru k.
Proteins. 2021 Sep;89(9):1099-1110. doi: 10.1002/prot.26083. Epub 2021 Apr 28.
Proteins. 2021.
PMID: 33843112
Free PMC article.
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General chemoenzymatic route to two-stereocenter triketides employing assembly line ketoreductases.
Zhang Z , Cepeda AJ , Robles ML , Hirsch M , Kumru K , Zhou JA , Keatinge-Clay AT .
Zhang Z , et al. Among authors: kumru k.
Chem Commun (Camb). 2019 Dec 17;56(1):157-160. doi: 10.1039/c9cc07966a.
Chem Commun (Camb). 2019.
PMID: 31799975
Free PMC article.
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