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Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence.
Mahoney SA, Venkatasubramanian R, Darrah MA, Ludwig KR, VanDongen NS, Greenberg NT, Longtine AG, Hutton DA, Brunt VE, Campisi J, Melov S, Seals DR, Rossman MJ, Clayton ZS. Mahoney SA, et al. Among authors: hutton da. Aging Cell. 2024 Mar;23(3):e14060. doi: 10.1111/acel.14060. Epub 2023 Dec 7. Aging Cell. 2024. PMID: 38062873 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35560440
Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment.
Clayton ZS, Rossman MJ, Mahoney SA, Venkatasubramanian R, Maurer GS, Hutton DA, VanDongen NS, Greenberg NT, Longtine AG, Ludwig KR, Brunt VE, LaRocca TJ, Campisi J, Melov S, Seals DR. Clayton ZS, et al. Among authors: hutton da. Hypertension. 2023 Oct;80(10):2072-2087. doi: 10.1161/HYPERTENSIONAHA.123.21392. Epub 2023 Aug 18. Hypertension. 2023. PMID: 37593877
Lifelong voluntary aerobic exercise prevents age- and Western diet- induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice.
Gioscia-Ryan RA, Clayton ZS, Zigler MC, Richey JJ, Cuevas LM, Rossman MJ, Battson ML, Ziemba BP, Hutton DA, VanDongen NS, Seals DR. Gioscia-Ryan RA, et al. Among authors: hutton da. J Physiol. 2021 Feb;599(3):911-925. doi: 10.1113/JP280607. Epub 2020 Oct 28. J Physiol. 2021. PMID: 33103241 Free PMC article.
Tumor Necrosis Factor Alpha-Mediated Inflammation and Remodeling of the Extracellular Matrix Underlies Aortic Stiffening Induced by the Common Chemotherapeutic Agent Doxorubicin.
Clayton ZS, Brunt VE, Hutton DA, Casso AG, Ziemba BP, Melov S, Campisi J, Seals DR. Clayton ZS, et al. Among authors: hutton da. Hypertension. 2021 May 5;77(5):1581-1590. doi: 10.1161/HYPERTENSIONAHA.120.16759. Epub 2021 Mar 15. Hypertension. 2021. PMID: 33719511 Free PMC article.
Apigenin restores endothelial function by ameliorating oxidative stress, reverses aortic stiffening, and mitigates vascular inflammation with aging.
Clayton ZS, Hutton DA, Brunt VE, VanDongen NS, Ziemba BP, Casso AG, Greenberg NT, Mercer AN, Rossman MJ, Campisi J, Melov S, Seals DR. Clayton ZS, et al. Among authors: hutton da. Am J Physiol Heart Circ Physiol. 2021 Jul 1;321(1):H185-H196. doi: 10.1152/ajpheart.00118.2021. Epub 2021 Jun 11. Am J Physiol Heart Circ Physiol. 2021. PMID: 34114892 Free PMC article.
45 results