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Tying a true topological protein knot by cyclization.
Biochem Biophys Res Commun. 2024 Feb 12;696:149470. doi: 10.1016/j.bbrc.2024.149470. Epub 2024 Jan 12.
Biochem Biophys Res Commun. 2024.
PMID: 38244314
Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING.
Hou MH, Wang YC, Yang CS, Liao KF, Chang JW, Shih O, Yeh YQ, Sriramoju MK, Weng TW, Jeng US, Hsu SD, Chen Y.
Hou MH, et al. Among authors: sriramoju mk.
Nat Commun. 2023 Dec 21;14(1):8519. doi: 10.1038/s41467-023-44052-x.
Nat Commun. 2023.
PMID: 38129386
Free PMC article.
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Structure, dynamics, and stability of the smallest and most complex 71 protein knot.
Hsu MF, Sriramoju MK, Lai CH, Chen YR, Huang JS, Ko TP, Huang KF, Hsu SD.
Hsu MF, et al. Among authors: sriramoju mk.
J Biol Chem. 2024 Jan;300(1):105553. doi: 10.1016/j.jbc.2023.105553. Epub 2023 Dec 10.
J Biol Chem. 2024.
PMID: 38072060
Free PMC article.
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A High-Throughput Interbacterial Competition Screen Identifies ClpAP in Enhancing Recipient Susceptibility to Type VI Secretion System-Mediated Attack by Agrobacterium tumefaciens.
Lin HH, Yu M, Sriramoju MK, Hsu SD, Liu CT, Lai EM.
Lin HH, et al. Among authors: sriramoju mk.
Front Microbiol. 2020 Feb 5;10:3077. doi: 10.3389/fmicb.2019.03077. eCollection 2019.
Front Microbiol. 2020.
PMID: 32117077
Free PMC article.
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Protein knots provide mechano-resilience to an AAA+ protease-mediated proteolysis with profound ATP energy expenses.
Sriramoju MK, Chen Y, Hsu SD.
Sriramoju MK, et al.
Biochim Biophys Acta Proteins Proteom. 2020 Feb;1868(2):140330. doi: 10.1016/j.bbapap.2019.140330. Epub 2019 Nov 20.
Biochim Biophys Acta Proteins Proteom. 2020.
PMID: 31756432
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Comparative folding analyses of unknotted versus trefoil-knotted ornithine transcarbamylases suggest stabilizing effects of protein knots.
Sriramoju MK, Yang TJ, Hsu SD.
Sriramoju MK, et al.
Biochem Biophys Res Commun. 2018 Sep 5;503(2):822-829. doi: 10.1016/j.bbrc.2018.06.082. Epub 2018 Jun 21.
Biochem Biophys Res Commun. 2018.
PMID: 29920242
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Topologically knotted deubiquitinases exhibit unprecedented mechanostability to withstand the proteolysis by an AAA+ protease.
Sriramoju MK, Chen Y, Lee YC, Hsu SD.
Sriramoju MK, et al.
Sci Rep. 2018 May 4;8(1):7076. doi: 10.1038/s41598-018-25470-0.
Sci Rep. 2018.
PMID: 29728659
Free PMC article.
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