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A missense variant in human perilipin 2 (PLIN2 Ser251Pro) reduces hepatic steatosis in mice.
Scorletti E, Saiman Y, Jeon S, Schneider CV, Buyco DG, Lin C, Himes BE, Mesaros CA, Vujkovic M, Creasy KT, Furth EE, Billheimer JT, Hand NJ, Kaplan DE, Chang KM, Tsao PS, Lynch JA, Dempsey JL, Harkin J, Bayen S, Conlon D, Guerraty M, Phillips MC, Rader DJ, Carr RM. Scorletti E, et al. Among authors: billheimer jt. JHEP Rep. 2023 Oct 11;6(1):100902. doi: 10.1016/j.jhepr.2023.100902. eCollection 2024 Jan. JHEP Rep. 2023. PMID: 38074507 Free PMC article.
ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease.
Ko YA, Billheimer JT, Lyssenko NN, Kueider-Paisley A, Wolk DA, Arnold SE, Leung YY, Shaw LM, Trojanowski JQ, Kaddurah-Daouk RF, Kling MA, Rader DJ. Ko YA, et al. Among authors: billheimer jt. Alzheimers Res Ther. 2022 Dec 26;14(1):194. doi: 10.1186/s13195-022-01119-z. Alzheimers Res Ther. 2022. PMID: 36572909 Free PMC article.
Specificity of ABCA7-mediated cell lipid efflux.
Picataggi A, Rodrigues A, Cromley DA, Wang H, Wiener JP, Garliyev V, Billheimer JT, Grabiner BC, Hurt JA, Chen AC, Han X, Rader DJ, Praticò D, Lyssenko NN. Picataggi A, et al. Among authors: billheimer jt. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Jul;1867(7):159157. doi: 10.1016/j.bbalip.2022.159157. Epub 2022 Apr 3. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 35381375 Free PMC article.
Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins.
Khetarpal SA, Vitali C, Levin MG, Klarin D, Park J, Pampana A, Millar JS, Kuwano T, Sugasini D, Subbaiah PV, Billheimer JT, Natarajan P, Rader DJ. Khetarpal SA, et al. Among authors: billheimer jt. PLoS Genet. 2021 Sep 20;17(9):e1009802. doi: 10.1371/journal.pgen.1009802. eCollection 2021 Sep. PLoS Genet. 2021. PMID: 34543263 Free PMC article.
Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease.
Cipollari E, Szapary HJ, Picataggi A, Billheimer JT, Lyssenko CA, Ying GS, Shaw LM, Kling MA, Kaddurah-Daouk R, Rader DJ, Praticò D, Lyssenko NN; Alzheimer’s Disease Metabolomics Consortium. Cipollari E, et al. Among authors: billheimer jt. J Alzheimers Dis. 2020;74(2):563-578. doi: 10.3233/JAD-191246. J Alzheimers Dis. 2020. PMID: 32065798 Free PMC article.
A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans.
Cuchel M, Raper AC, Conlon DM, Pryma DA, Freifelder RH, Poria R, Cromley D, Li X, Dunbar RL, French B, Qu L, Farver W, Su CC, Lund-Katz S, Baer A, Ruotolo G, Akerblad P, Ryan CS, Xiao L, Kirchgessner TG, Millar JS, Billheimer JT, Rader DJ. Cuchel M, et al. Among authors: billheimer jt. J Lipid Res. 2017 Apr;58(4):752-762. doi: 10.1194/jlr.M075226. Epub 2017 Feb 6. J Lipid Res. 2017. PMID: 28167703 Free PMC article.
Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport.
Kuwano T, Bi X, Cipollari E, Yasuda T, Lagor WR, Szapary HJ, Tohyama J, Millar JS, Billheimer JT, Lyssenko NN, Rader DJ. Kuwano T, et al. Among authors: billheimer jt. J Lipid Res. 2017 Apr;58(4):731-741. doi: 10.1194/jlr.M074625. Epub 2017 Jan 30. J Lipid Res. 2017. PMID: 28137768 Free PMC article.
113 results