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AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress.
Torres Acosta MA, Mambetsariev N, Reyes Flores CP, Helmin KA, Liu Q, Joudi AM, Morales-Nebreda L, Gurkan J, Cheng K, Abdala-Valencia H, Weinberg SE, Singer BD. Torres Acosta MA, et al. Among authors: abdala valencia h. bioRxiv [Preprint]. 2023 Dec 1:2023.11.29.568904. doi: 10.1101/2023.11.29.568904. bioRxiv. 2023. PMID: 38076988 Free PMC article. Preprint.
Regulation of allergic lung inflammation by endothelial cell transglutaminase 2.
Soveg F, Abdala-Valencia H, Campbell J, Morales-Nebreda L, Mutlu GM, Cook-Mills JM. Soveg F, et al. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15;309(6):L573-83. doi: 10.1152/ajplung.00199.2015. Epub 2015 Jul 24. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 26209276 Free PMC article.
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.
Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Gates K, Lam AP, Nicholson TT, Homan PJ, Soberanes S, Dominguez S, Morgan VK, Saber R, Shaffer A, Hinchcliff M, Marshall SA, Bharat A, Berdnikovs S, Bhorade SM, Bartom ET, Morimoto RI, Balch WE, Sznajder JI, Chandel NS, Mutlu GM, Jain M, Gottardi CJ, Singer BD, Ridge KM, Bagheri N, Shilatifard A, Budinger GRS, Perlman H. Misharin AV, et al. J Exp Med. 2017 Aug 7;214(8):2387-2404. doi: 10.1084/jem.20162152. Epub 2017 Jul 10. J Exp Med. 2017. PMID: 28694385 Free PMC article.
Mitochondrial complex III is essential for suppressive function of regulatory T cells.
Weinberg SE, Singer BD, Steinert EM, Martinez CA, Mehta MM, Martínez-Reyes I, Gao P, Helmin KA, Abdala-Valencia H, Sena LA, Schumacker PT, Turka LA, Chandel NS. Weinberg SE, et al. Nature. 2019 Jan;565(7740):495-499. doi: 10.1038/s41586-018-0846-z. Epub 2019 Jan 9. Nature. 2019. PMID: 30626970 Free PMC article.
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Querrey M, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Lomasney JW, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith SB, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GRS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w. Epub 2021 Jan 11. Nature. 2021. PMID: 33429418 Free PMC article.
The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging.
McQuattie-Pimentel AC, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, Lu Z, Sichizya L, Aillon RP, Chen CI, Soberanes S, Chen Z, Reyfman PA, Walter JM, Anekalla KR, Davis JM, Helmin KA, Runyan CE, Abdala-Valencia H, Nam K, Meliton AY, Winter DR, Morimoto RI, Mutlu GM, Bharat A, Perlman H, Gottardi CJ, Ridge KM, Chandel NS, Sznajder JI, Balch WE, Singer BD, Misharin AV, Budinger GRS. McQuattie-Pimentel AC, et al. J Clin Invest. 2021 Feb 15;131(4):e140299. doi: 10.1172/JCI140299. J Clin Invest. 2021. PMID: 33586677 Free PMC article.
83 results