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The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.
Chang Q, Bournazou E, Sansone P, Berishaj M, Gao SP, Daly L, Wels J, Theilen T, Granitto S, Zhang X, Cotari J, Alpaugh ML, de Stanchina E, Manova K, Li M, Bonafe M, Ceccarelli C, Taffurelli M, Santini D, Altan-Bonnet G, Kaplan R, Norton L, Nishimoto N, Huszar D, Lyden D, Bromberg J. Chang Q, et al. Among authors: lyden d. Neoplasia. 2013 Jul;15(7):848-62. doi: 10.1593/neo.13706. Neoplasia. 2013. PMID: 23814496 Free PMC article.
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.
Thompson EM, Hielscher T, Bouffet E, Remke M, Luu B, Gururangan S, McLendon RE, Bigner DD, Lipp ES, Perreault S, Cho YJ, Grant G, Kim SK, Lee JY, Rao AAN, Giannini C, Li KKW, Ng HK, Yao Y, Kumabe T, Tominaga T, Grajkowska WA, Perek-Polnik M, Low DCY, Seow WT, Chang KTE, Mora J, Pollack IF, Hamilton RL, Leary S, Moore AS, Ingram WJ, Hallahan AR, Jouvet A, Fèvre-Montange M, Vasiljevic A, Faure-Conter C, Shofuda T, Kagawa N, Hashimoto N, Jabado N, Weil AG, Gayden T, Wataya T, Shalaby T, Grotzer M, Zitterbart K, Sterba J, Kren L, Hortobágyi T, Klekner A, László B, Pócza T, Hauser P, Schüller U, Jung S, Jang WY, French PJ, Kros JM, van Veelen MC, Massimi L, Leonard JR, Rubin JB, Vibhakar R, Chambless LB, Cooper MK, Thompson RC, Faria CC, Carvalho A, Nunes S, Pimentel J, Fan X, Muraszko KM, López-Aguilar E, Lyden D, Garzia L, Shih DJH, Kijima N, Schneider C, Adamski J, Northcott PA, Kool M, Jones DTW, Chan JA, Nikolic A, Garre ML, Van Meir EG, Osuka S, Olson JJ, Jahangiri A, Castro BA, Gupta N, Weiss WA, Moxon-Emre I, Mabbott DJ, Lassaletta A, Hawkins CE, Tabori U, Drake J, Kulkarni A, Dirks P, Rutka JT, Korshunov A, Pfister SM, Packer RJ, Ramaswamy V, Taylor MD. Thompson EM, et al. Among authors: lyden d. Lancet Oncol. 2016 Apr;17(4):484-495. doi: 10.1016/S1470-2045(15)00581-1. Epub 2016 Mar 12. Lancet Oncol. 2016. PMID: 26976201 Free PMC article.
A Genomic-Pathologic Annotated Risk Model to Predict Recurrence in Early-Stage Lung Adenocarcinoma.
Jones GD, Brandt WS, Shen R, Sanchez-Vega F, Tan KS, Martin A, Zhou J, Berger M, Solit DB, Schultz N, Rizvi H, Liu Y, Adamski A, Chaft JE, Riely GJ, Rocco G, Bott MJ, Molena D, Ladanyi M, Travis WD, Rekhtman N, Park BJ, Adusumilli PS, Lyden D, Imielinski M, Mayo MW, Li BT, Jones DR. Jones GD, et al. Among authors: lyden d. JAMA Surg. 2021 Feb 1;156(2):e205601. doi: 10.1001/jamasurg.2020.5601. Epub 2021 Feb 10. JAMA Surg. 2021. PMID: 33355651 Free PMC article.
STAT3 negatively regulates thyroid tumorigenesis.
Couto JP, Daly L, Almeida A, Knauf JA, Fagin JA, Sobrinho-Simões M, Lima J, Máximo V, Soares P, Lyden D, Bromberg JF. Couto JP, et al. Among authors: lyden d. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2361-70. doi: 10.1073/pnas.1201232109. Epub 2012 Aug 13. Proc Natl Acad Sci U S A. 2012. PMID: 22891351 Free PMC article.
The Id proteins and angiogenesis.
Benezra R, Rafii S, Lyden D. Benezra R, et al. Among authors: lyden d. Oncogene. 2001 Dec 20;20(58):8334-41. doi: 10.1038/sj.onc.1205160. Oncogene. 2001. PMID: 11840326 Review.
A genetic approach to understanding tumor angiogenesis.
Benezra R, de Candia P, Li H, Romero E, Lyden D, Rafii S, Ruzinova M. Benezra R, et al. Among authors: lyden d. Cold Spring Harb Symp Quant Biol. 2002;67:249-54. doi: 10.1101/sqb.2002.67.249. Cold Spring Harb Symp Quant Biol. 2002. PMID: 12858547 No abstract available.
147 results