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Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs).
J Med Chem. 2023 Dec 28;66(24):16704-16727. doi: 10.1021/acs.jmedchem.3c01406. Epub 2023 Dec 14.
J Med Chem. 2023.
PMID: 38096366
Free article.
Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development.
Lewandowski CT, Khan MW, BenAissa M, Dubrovskyi O, Ackerman-Berrier M, LaDu MJ, Layden BT, Thatcher GRJ.
Lewandowski CT, et al. Among authors: ackerman berrier m.
EBioMedicine. 2021 Apr;66:103287. doi: 10.1016/j.ebiom.2021.103287. Epub 2021 Mar 19.
EBioMedicine. 2021.
PMID: 33752129
Free PMC article.
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Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD.
Ratia KM, Shen Z, Gordon-Blake J, Lee H, Laham MS, Krider IS, Christie N, Ackerman-Berrier M, Penton C, Knowles NG, Musku SR, Fu J, Velma GR, Xiong R, Thatcher GRJ.
Ratia KM, et al. Among authors: ackerman berrier m.
Biochemistry. 2023 Feb 21;62(4):923-933. doi: 10.1021/acs.biochem.2c00655. Epub 2023 Feb 6.
Biochemistry. 2023.
PMID: 36746631
Free PMC article.
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Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress.
Gordon-Blake J, Ratia K, Weidig V, Velma GR, Ackerman-Berrier M, Penton C, Musku SR, Alves ETM, Driver T, Tai L, Thatcher GRJ.
Gordon-Blake J, et al. Among authors: ackerman berrier m.
ACS Med Chem Lett. 2024 Jan 24;15(2):205-214. doi: 10.1021/acsmedchemlett.3c00391. eCollection 2024 Feb 8.
ACS Med Chem Lett. 2024.
PMID: 38352833
Free PMC article.
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Efficient discovery of inhibitory ligands for diverse targets from a small combinatorial chemical library of chimeric molecules.
Thorpe DS, Edith Chan AW, Binnie A, Chen LC, Robinson A, Spoonamore J, Rodwell D, Wade S, Wilson S, Ackerman-Berrier M, Yeoman H, Walle S, Wu Q, Wertman KF.
Thorpe DS, et al. Among authors: ackerman berrier m.
Biochem Biophys Res Commun. 1999 Dec 9;266(1):62-5. doi: 10.1006/bbrc.1999.1775.
Biochem Biophys Res Commun. 1999.
PMID: 10581165
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