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Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs).
J Med Chem. 2023 Dec 28;66(24):16704-16727. doi: 10.1021/acs.jmedchem.3c01406. Epub 2023 Dec 14.
J Med Chem. 2023.
PMID: 38096366
Free article.
Remembering your A, B, C's: Alzheimer's disease and ABCA1.
Lewandowski CT, Laham MS, Thatcher GRJ.
Lewandowski CT, et al. Among authors: laham ms.
Acta Pharm Sin B. 2022 Mar;12(3):995-1018. doi: 10.1016/j.apsb.2022.01.011. Epub 2022 Jan 24.
Acta Pharm Sin B. 2022.
PMID: 35530134
Free PMC article.
Review.
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Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD.
Ratia KM, Shen Z, Gordon-Blake J, Lee H, Laham MS, Krider IS, Christie N, Ackerman-Berrier M, Penton C, Knowles NG, Musku SR, Fu J, Velma GR, Xiong R, Thatcher GRJ.
Ratia KM, et al. Among authors: laham ms.
Biochemistry. 2023 Feb 21;62(4):923-933. doi: 10.1021/acs.biochem.2c00655. Epub 2023 Feb 6.
Biochemistry. 2023.
PMID: 36746631
Free PMC article.
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Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death.
Velma GR, Krider IS, Alves ETM, Courey JM, Laham MS, Thatcher GRJ.
Velma GR, et al. Among authors: laham ms.
J Med Chem. 2024 Apr 25;67(8):5999-6026. doi: 10.1021/acs.jmedchem.3c02112. Epub 2024 Apr 5.
J Med Chem. 2024.
PMID: 38580317
Free PMC article.
Review.
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