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Full-length MSP1 is a major target of protective immunity after controlled human malaria infection.
Life Sci Alliance. 2024 May 20;7(8):e202301910. doi: 10.26508/lsa.202301910. Print 2024 Aug.
Life Sci Alliance. 2024.
PMID: 38803222
Free PMC article.
Breadth of Fc-mediated effector function correlates with clinical immunity following human malaria challenge.
Nkumama IN, Ogwang R, Odera D, Musasia F, Mwai K, Nyamako L, Murungi L, Tuju J, Fürle K, Rosenkranz M, Kimathi R, Njuguna P, Hamaluba M, Kapulu MC, Frank R; CHMI-SIKA study team; Osier FHA.
Nkumama IN, et al. Among authors: furle k.
Immunity. 2024 May 21:S1074-7613(24)00233-4. doi: 10.1016/j.immuni.2024.05.001. Online ahead of print.
Immunity. 2024.
PMID: 38788711
Free article.
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IgG Subclass Switch in Volunteers Repeatedly Immunized with the Full-Length Plasmodium falciparum Merozoite Surface Protein 1 (MSP1).
Rathay V, Fürle K, Kiehl V, Ulmer A, Lanzer M, Thomson-Luque R.
Rathay V, et al. Among authors: furle k.
Vaccines (Basel). 2024 Feb 17;12(2):208. doi: 10.3390/vaccines12020208.
Vaccines (Basel). 2024.
PMID: 38400191
Free PMC article.
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Plasmodium falciparum merozoite surface protein 1 as asexual blood stage malaria vaccine candidate.
Thomson-Luque R, Stabler TC, Fürle K, Silva JC, Daubenberger C.
Thomson-Luque R, et al. Among authors: furle k.
Expert Rev Vaccines. 2024 Jan-Dec;23(1):160-173. doi: 10.1080/14760584.2023.2295430. Epub 2023 Dec 27.
Expert Rev Vaccines. 2024.
PMID: 38100310
Free article.
Review.
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Multifunctional IgG/IgM antibodies and cellular cytotoxicity are elicited by the full-length MSP1 SumayaVac-1 malaria vaccine.
Rosenkranz M, Fürle K, Hibbert J, Ulmer A, Ali A, Giese T, Blank A, Haefeli WE, Böhnlein E, Lanzer M, Thomson-Luque R.
Rosenkranz M, et al. Among authors: furle k.
NPJ Vaccines. 2023 Aug 9;8(1):112. doi: 10.1038/s41541-023-00701-2.
NPJ Vaccines. 2023.
PMID: 37558673
Free PMC article.
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Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria.
Odera DO, Tuju J, Mwai K, Nkumama IN, Fürle K, Chege T, Kimathi R, Diehl S, Musasia FK, Rosenkranz M, Njuguna P, Hamaluba M, Kapulu MC, Frank R; CHMI-SIKA Study Team; Osier FHA, Abdi AI, Chi PC, de Laurent Z, Jao I, Kamuya D, Kamuyu G, Makale J, Murungi L, Musyoki J, Muthui M, Mwacharo J, Kariuki S, Mwanga D, Mwongeli J, Ndungu F, Njue M, Nyangweso G, Kimani D, Ngoi JM, Musembi J, Ngoto O, Otieno E, Ooko M, Shangala J, Wambua J, Mohammed KS, Omuoyo D, Mosobo M, Kibinge N, Kinyanjui S, Bejon P, Lowe B, Marsh K, Marsh V, Abebe Y, Billingsley PF, Sim BKL, Hoffman SL, James ER, Richie TL, Audi A, Olewe F, Oloo J, Ongecha J, Ongas MO, Koskei N, Bull PC, Hodgson SH, Kivisi C, Imwong M, Murphy SC, Ogutu B, Tarning J, Winterberg M, Williams TN.
Odera DO, et al. Among authors: furle k.
Sci Transl Med. 2023 Feb 8;15(682):eabn5993. doi: 10.1126/scitranslmed.abn5993. Epub 2023 Feb 8.
Sci Transl Med. 2023.
PMID: 36753561
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Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria.
Musasia FK, Nkumama IN, Frank R, Kipkemboi V, Schneider M, Mwai K, Odera DO, Rosenkranz M, Fürle K, Kimani D, Tuju J, Njuguna P, Hamaluba M, Kapulu MC, Wardemann H; CHMI-SIKA Study Team; Osier FHA.
Musasia FK, et al. Among authors: furle k.
Nat Commun. 2022 Jul 14;13(1):4098. doi: 10.1038/s41467-022-31640-6.
Nat Commun. 2022.
PMID: 35835738
Free PMC article.
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Immunization with full-length Plasmodium falciparum merozoite surface protein 1 is safe and elicits functional cytophilic antibodies in a randomized first-in-human trial.
Blank A, Fürle K, Jäschke A, Mikus G, Lehmann M, Hüsing J, Heiss K, Giese T, Carter D, Böhnlein E, Lanzer M, Haefeli WE, Bujard H.
Blank A, et al. Among authors: furle k.
NPJ Vaccines. 2020 Jan 31;5(1):10. doi: 10.1038/s41541-020-0160-2. eCollection 2020.
NPJ Vaccines. 2020.
PMID: 32025341
Free PMC article.
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