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Electroretinography and suicidal behaviors: a systematic review.
Kaggwa MM, Prat S, Davids A, Robbins A, Erb B, Mamak M, Chaimowitz GA, Olagunju AT. Kaggwa MM, et al. Among authors: erb b. BMC Psychiatry. 2023 Dec 15;23(1):948. doi: 10.1186/s12888-023-05453-w. BMC Psychiatry. 2023. PMID: 38102572 Free PMC article.
A consensus molecular subtypes classification strategy for clinical colorectal cancer tissues.
de Back TR, Wu T, Schafrat PJ, Ten Hoorn S, Tan M, He L, van Hooff SR, Koster J, Nijman LE, Vink GR, Beumer IJ, Elbers CC, Lenos KJ, Sommeijer DW, Wang X, Vermeulen L. de Back TR, et al. Life Sci Alliance. 2024 May 23;7(8):e202402730. doi: 10.26508/lsa.202402730. Print 2024 Aug. Life Sci Alliance. 2024. PMID: 38782602 Free PMC article.
Here, we present an FFPE-curated CMS classifier. The CMSFFPE classifier was developed using genes with a high transcript integrity in FFPE-derived RNA. We evaluated the classification accuracy in two FFPE-RNA datasets with matched fresh-frozen (FF) RNA data, and an FF-deri …
Here, we present an FFPE-curated CMS classifier. The CMSFFPE classifier was developed using genes with a high transcript integrity in …
Next-generation Sequencing of MicroRNA in Acquired Middle Ear Cholesteatoma.
Han SJ, Kim SK, Hong SM. Han SJ, et al. Laryngoscope. 2024 May 22. doi: 10.1002/lary.31507. Online ahead of print. Laryngoscope. 2024. PMID: 38775212
Total RNA was extracted, and miRNA expression profiles were analyzed by NGS technology. Functional gene classification to predict target genes and relevant biological pathways was performed using DIANA-microT-CDS and the Kyoto Encyclopedia Gene and Genome database (KEGG) p …
Total RNA was extracted, and miRNA expression profiles were analyzed by NGS technology. Functional gene classification to predict target …
Clinical relevance of somatic mutations in Chinese lung adenocarcinoma and their prognostic implications for survival.
Li T, Liu J, Zhou Y, Huang S, Wang D, Chen J, Fu Y, He P. Li T, et al. Cancer Med. 2024 May;13(10):e7227. doi: 10.1002/cam4.7227. Cancer Med. 2024. PMID: 38770632 Free PMC article.
The Cox regression analysis was employed to identify prognosis-related genes and establish a predictive model for stratifying patients with LUAD. ...We developed a Multiple Parameter Gene Mutation (MPGM) risk model by integrating critical genes and oncogenic pathway …
The Cox regression analysis was employed to identify prognosis-related genes and establish a predictive model for stratifying patient …
Reverse repurposing: Potential utility of cancer drugs in nonmalignant illnesses.
Nikanjam M, Wells K, Kato S, Adashek JJ, Block S, Kurzrock R. Nikanjam M, et al. Med. 2024 May 9:S2666-6340(24)00178-8. doi: 10.1016/j.medj.2024.04.008. Online ahead of print. Med. 2024. PMID: 38749442 Review.
MEK, PI3K/AKT/mTOR, fibroblast growth factor receptor (FGFR), and NRG1/ERBB pathway genes have all been implicated in both cancer and noncancerous conditions, and several cognate antagonists, as well as Bruton's tyrosine kinase inhibitors, JAK inhibitors, and CD20-d …
MEK, PI3K/AKT/mTOR, fibroblast growth factor receptor (FGFR), and NRG1/ERBB pathway genes have all been implicated in both can …
Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2-Positive Advanced Gastric Cancer.
Yamaguchi K, Ito M, Isobe T, Koreishi S, Taguchi R, Uehara K, Ueno S, Imajima T, Kitazono T, Tsuchihashi K, Ohmura H, Yoshihiro T, Tanoue K, Nishiyori S, Iwama E, Maeda T, Akashi K, Baba E. Yamaguchi K, et al. JCO Precis Oncol. 2024 May;8:e2300681. doi: 10.1200/PO.23.00681. JCO Precis Oncol. 2024. PMID: 38748981
RESULTS: In 114 patients with human epidermal growth factor receptor-2 (HER2)-positive G/GEJ cancer treated with T-DXd, the most frequently altered genes were TP53 (82%), ERBB2 (80%), and CCNE1 (36%). Multivariate Cox regression analysis revealed CCNE1 amplification to be …
RESULTS: In 114 patients with human epidermal growth factor receptor-2 (HER2)-positive G/GEJ cancer treated with T-DXd, the most frequently …
CD133 Stimulates Cell Proliferation via the Upregulation of Amphiregulin in Melanoma.
Simbulan-Rosenthal CM, Islam N, Haribabu Y, Alobaidi R, Shalamzari A, Graham G, Kuo LW, Sykora P, Rosenthal DS. Simbulan-Rosenthal CM, et al. Cells. 2024 May 2;13(9):777. doi: 10.3390/cells13090777. Cells. 2024. PMID: 38727313 Free PMC article.
Cells were exposed to Dox for 24 h to induce CD133 expression, followed by RNA-seq and bioinformatic analyses, revealing genes and pathways that are significantly up- or downregulated by CD133. ...
Cells were exposed to Dox for 24 h to induce CD133 expression, followed by RNA-seq and bioinformatic analyses, revealing genes and pa …
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