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De novo design of high-affinity binders of bioactive helical peptides.
Vázquez Torres S, Leung PJY, Venkatesh P, Lutz ID, Hink F, Huynh HH, Becker J, Yeh AH, Juergens D, Bennett NR, Hoofnagle AN, Huang E, MacCoss MJ, Expòsit M, Lee GR, Bera AK, Kang A, De La Cruz J, Levine PM, Li X, Lamb M, Gerben SR, Murray A, Heine P, Korkmaz EN, Nivala J, Stewart L, Watson JL, Rogers JM, Baker D. Vázquez Torres S, et al. Among authors: huang e. Nature. 2024 Feb;626(7998):435-442. doi: 10.1038/s41586-023-06953-1. Epub 2023 Dec 18. Nature. 2024. PMID: 38109936 Free PMC article.
Elamipretide (SS-31) treatment attenuates age-associated post-translational modifications of heart proteins.
Whitson JA, Martín-Pérez M, Zhang T, Gaffrey MJ, Merrihew GE, Huang E, White CC, Kavanagh TJ, Qian WJ, Campbell MD, MacCoss MJ, Marcinek DJ, Villén J, Rabinovitch PS. Whitson JA, et al. Among authors: huang e. Geroscience. 2021 Oct;43(5):2395-2412. doi: 10.1007/s11357-021-00447-6. Epub 2021 Sep 4. Geroscience. 2021. PMID: 34480713 Free PMC article.
CD8+ tissue-resident memory T cells are expanded in primary Sjögren's disease and can be therapeutically targeted by CD103 blockade.
Mauro D, Lin X, Pontarini E, Wehr P, Guggino G, Tang Y, Deng C, Gandolfo S, Xiao F, Rui K, Huang E, Tian J, Raimondo S, Rischmueller M, Boroky J, Downie-Doyle S, Nel H, Baz-Morelli A, Hsu A, Maraskovsky E, Barr A, Hemon P, Chatzis L, Boschetti CE, Colella G, Alessandro R, Rizzo A, Pers JO, Bombardieri M, Thomas R, Lu L, Ciccia F. Mauro D, et al. Among authors: huang e. Ann Rheum Dis. 2024 May 22:ard-2023-225069. doi: 10.1136/ard-2023-225069. Online ahead of print. Ann Rheum Dis. 2024. PMID: 38777379
2,576 results