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Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Kath J, et al. Among authors: abken h. bioRxiv [Preprint]. 2023 Nov 14:2023.11.10.565518. doi: 10.1101/2023.11.10.565518. bioRxiv. 2023. PMID: 38116030 Free PMC article. Updated. Preprint.
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Kath J, et al. Among authors: abken h. Blood. 2024 Mar 17:blood.2023020973. doi: 10.1182/blood.2023020973. Online ahead of print. Blood. 2024. PMID: 38493479 Free article.
Nanobody Based Dual Specific CARs.
De Munter S, Ingels J, Goetgeluk G, Bonte S, Pille M, Weening K, Kerre T, Abken H, Vandekerckhove B. De Munter S, et al. Among authors: abken h. Int J Mol Sci. 2018 Jan 30;19(2):403. doi: 10.3390/ijms19020403. Int J Mol Sci. 2018. PMID: 29385713 Free PMC article.
Generation of an NFκB-Driven Alpharetroviral "All-in-One" Vector Construct as a Potent Tool for CAR NK Cell Therapy.
Rudek LS, Zimmermann K, Galla M, Meyer J, Kuehle J, Stamopoulou A, Brand D, Sandalcioglu IE, Neyazi B, Moritz T, Rossig C, Altvater B, Falk CS, Abken H, Morgan MA, Schambach A. Rudek LS, et al. Among authors: abken h. Front Immunol. 2021 Nov 3;12:751138. doi: 10.3389/fimmu.2021.751138. eCollection 2021. Front Immunol. 2021. PMID: 34804035 Free PMC article.
TRUCKs: the fourth generation of CARs.
Chmielewski M, Abken H. Chmielewski M, et al. Among authors: abken h. Expert Opin Biol Ther. 2015;15(8):1145-54. doi: 10.1517/14712598.2015.1046430. Epub 2015 May 18. Expert Opin Biol Ther. 2015. PMID: 25985798 Review.
225 results