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NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils.
Zhu YP, Speir M, Tan Z, Lee JC, Nowell CJ, Chen AA, Amatullah H, Salinger AJ, Huang CJ, Wu G, Peng W, Askari K, Griffis E, Ghassemian M, Santini J, Gerlic M, Kiosses WB, Catz SD, Hoffman HM, Greco KF, Weller E, Thompson PR, Wong LP, Sadreyev R, Jeffrey KL, Croker BA. Zhu YP, et al. Among authors: croker ba. Sci Adv. 2023 Dec 22;9(51):eadj1397. doi: 10.1126/sciadv.adj1397. Epub 2023 Dec 20. Sci Adv. 2023. PMID: 38117877 Free PMC article.
The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils.
D'Cruz AA, Speir M, Bliss-Moreau M, Dietrich S, Wang S, Chen AA, Gavillet M, Al-Obeidi A, Lawlor KE, Vince JE, Kelliher MA, Hakem R, Pasparakis M, Williams DA, Ericsson M, Croker BA. D'Cruz AA, et al. Among authors: croker ba. Sci Signal. 2018 Sep 4;11(546):eaao1716. doi: 10.1126/scisignal.aao1716. Sci Signal. 2018. PMID: 30181240 Free PMC article.
Myelopoiesis embraces its inner weakness.
Gerlic M, Croker BA. Gerlic M, et al. Among authors: croker ba. Nat Immunol. 2017 Aug 22;18(9):953-954. doi: 10.1038/ni.3814. Nat Immunol. 2017. PMID: 28829446 Free PMC article.
Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Speir M, Nowell CJ, Chen AA, O'Donnell JA, Shamie IS, Lakin PR, D'Cruz AA, Braun RO, Babon JJ, Lewis RS, Bliss-Moreau M, Shlomovitz I, Wang S, Cengia LH, Stoica AI, Hakem R, Kelliher MA, O'Reilly LA, Patsiouras H, Lawlor KE, Weller E, Lewis NE, Roberts AW, Gerlic M, Croker BA. Speir M, et al. Among authors: croker ba. Nat Immunol. 2020 Jan;21(1):54-64. doi: 10.1038/s41590-019-0550-7. Epub 2019 Dec 9. Nat Immunol. 2020. PMID: 31819256 Free PMC article.
Walking down the memory lane with SARS-CoV-2 B cells.
Freund NT, Gerlic M, Croker BA. Freund NT, et al. Among authors: croker ba. Immunol Cell Biol. 2021 Sep;99(8):796-799. doi: 10.1111/imcb.12494. Epub 2021 Aug 6. Immunol Cell Biol. 2021. PMID: 34355822 Free PMC article.
Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C.
Zhu YP, Shamie I, Lee JC, Nowell CJ, Peng W, Angulo S, Le LN, Liu Y, Miao H, Xiong H, Pena CJ, Moreno E, Griffis E, Labou SG, Franco A, Broderick L, Hoffman HM, Shimizu C, Lewis NE, Kanegaye JT, Tremoulet AH, Burns JC, Croker BA; Pediatric Emergency Medicine Kawasaki Disease Research Group Consortium. Zhu YP, et al. Among authors: croker ba. J Clin Invest. 2021 Oct 15;131(20):e147076. doi: 10.1172/JCI147076. J Clin Invest. 2021. PMID: 34464357 Free PMC article.
Pyroptotic death storms and cytopenia.
Croker BA, O'Donnell JA, Gerlic M. Croker BA, et al. Curr Opin Immunol. 2014 Feb;26:128-37. doi: 10.1016/j.coi.2013.12.002. Epub 2013 Dec 22. Curr Opin Immunol. 2014. PMID: 24556409 Review.
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