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Page 1
Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes.
Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein MY, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Krüger M, Frezza C, Heeren J, Trifunovic A, Pasparakis M. Moschandrea C, et al. Among authors: brodesser s. Nature. 2024 Jan;625(7994):385-392. doi: 10.1038/s41586-023-06857-0. Epub 2023 Dec 20. Nature. 2024. PMID: 38123683 Free PMC article.
Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function.
Oliverio M, Schmidt E, Mauer J, Baitzel C, Hansmeier N, Khani S, Konieczka S, Pradas-Juni M, Brodesser S, Van TM, Bartsch D, Brönneke HS, Heine M, Hilpert H, Tarcitano E, Garinis GA, Frommolt P, Heeren J, Mori MA, Brüning JC, Kornfeld JW. Oliverio M, et al. Among authors: brodesser s. Nat Cell Biol. 2016 Mar;18(3):328-36. doi: 10.1038/ncb3316. Epub 2016 Feb 22. Nat Cell Biol. 2016. PMID: 26900752
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth.
Schiffmann LM, Werthenbach JP, Heintges-Kleinhofer F, Seeger JM, Fritsch M, Günther SD, Willenborg S, Brodesser S, Lucas C, Jüngst C, Albert MC, Schorn F, Witt A, Moraes CT, Bruns CJ, Pasparakis M, Krönke M, Eming SA, Coutelle O, Kashkar H. Schiffmann LM, et al. Among authors: brodesser s. Nat Commun. 2020 Jul 21;11(1):3653. doi: 10.1038/s41467-020-17472-2. Nat Commun. 2020. PMID: 32694534 Free PMC article.
Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein.
Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M. Aravamudhan S, et al. Among authors: brodesser s. J Mol Cell Cardiol. 2021 May;154:41-59. doi: 10.1016/j.yjmcc.2021.01.010. Epub 2021 Feb 5. J Mol Cell Cardiol. 2021. PMID: 33549681 Free article.
Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR.
Kaspar S, Oertlin C, Szczepanowska K, Kukat A, Senft K, Lucas C, Brodesser S, Hatzoglou M, Larsson O, Topisirovic I, Trifunovic A. Kaspar S, et al. Among authors: brodesser s. Sci Adv. 2021 May 26;7(22):eabf0971. doi: 10.1126/sciadv.abf0971. Print 2021 May. Sci Adv. 2021. PMID: 34039602 Free PMC article.
Organ Protection by Caloric Restriction Depends on Activation of the De Novo NAD+ Synthesis Pathway.
Späth MR, Hoyer-Allo KJR, Seufert L, Höhne M, Lucas C, Bock T, Isermann L, Brodesser S, Lackmann JW, Kiefer K, Koehler FC, Bohl K, Ignarski M, Schiller P, Johnsen M, Kubacki T, Grundmann F, Benzing T, Trifunovic A, Krüger M, Schermer B, Burst V, Müller RU. Späth MR, et al. Among authors: brodesser s. J Am Soc Nephrol. 2023 May 1;34(5):772-792. doi: 10.1681/ASN.0000000000000087. Epub 2023 Feb 9. J Am Soc Nephrol. 2023. PMID: 36758124 Free PMC article.
IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart.
Nanadikar MS, Vergel Leon AM, Guo J, van Belle GJ, Jatho A, Philip ES, Brandner AF, Böckmann RA, Shi R, Zieseniss A, Siemssen CM, Dettmer K, Brodesser S, Schmidtendorf M, Lee J, Wu H, Furdui CM, Brandenburg S, Burgoyne JR, Bogeski I, Riemer J, Chowdhury A, Rehling P, Bruegmann T, Belousov VV, Katschinski DM. Nanadikar MS, et al. Among authors: brodesser s. Nat Commun. 2023 Apr 14;14(1):2123. doi: 10.1038/s41467-023-37744-x. Nat Commun. 2023. PMID: 37055412 Free PMC article.
CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice.
Hammerschmidt P, Steculorum SM, Bandet CL, Del Río-Martín A, Steuernagel L, Kohlhaas V, Feldmann M, Varela L, Majcher A, Quatorze Correia M, Klar RFU, Bauder CA, Kaya E, Porniece M, Biglari N, Sieben A, Horvath TL, Hornemann T, Brodesser S, Brüning JC. Hammerschmidt P, et al. Among authors: brodesser s. Nat Commun. 2023 Nov 29;14(1):7824. doi: 10.1038/s41467-023-42595-7. Nat Commun. 2023. PMID: 38016943 Free PMC article.
68 results