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Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
Subbiah V, Coleman N, Piha-Paul SA, Tsimberidou AM, Janku F, Rodon J, Pant S, Dumbrava EEI, Fu S, Hong DS, Zhang S, Sun M, Jiang Y, Roszik J, Song J, Yuan Y, Meric-Bernstam F, Naing A. Subbiah V, et al. Among authors: coleman n. Cancer Res Commun. 2024 Feb 12;4(2):378-387. doi: 10.1158/2767-9764.CRC-22-0260. Cancer Res Commun. 2024. PMID: 38126764 Free PMC article. Clinical Trial.
Taking Aim at the Undruggable.
Coleman N, Rodon J. Coleman N, et al. Am Soc Clin Oncol Educ Book. 2021 Mar;41:1-8. doi: 10.1200/EDBK_325885. Am Soc Clin Oncol Educ Book. 2021. PMID: 33989024 Free article.
HRAS Mutations Define a Distinct Subgroup in Head and Neck Squamous Cell Carcinoma.
Coleman N, Marcelo KL, Hopkins JF, Khan NI, Du R, Hong L, Park E, Balsara B, Leoni M, Pickering C, Myers J, Heymach J, Albacker LA, Hong D, Gillison M, Le X. Coleman N, et al. JCO Precis Oncol. 2023 Jan;7:e2200211. doi: 10.1200/PO.22.00211. JCO Precis Oncol. 2023. PMID: 36603172 Free PMC article.
Landscape and Clonal Dominance of Co-occurring Genomic Alterations in Non-Small-Cell Lung Cancer Harboring MET Exon 14 Skipping.
Le X, Hong L, Hensel C, Chen R, Kemp H, Coleman N, Ciunci CA, Liu SV, Negrao MV, Yen J, Xia X, Scheuenpflug J, Stroh C, Juraeva D, Tsao A, Hong D, Raymond V, Paik P, Zhang J, Heymach JV. Le X, et al. Among authors: coleman n. JCO Precis Oncol. 2021 Dec 13;5:PO.21.00135. doi: 10.1200/PO.21.00135. eCollection 2021. JCO Precis Oncol. 2021. PMID: 34957368 Free PMC article.
650 results