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A genome-wide association study meta-analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci.
De Almeida SD, Richter GM, de Coo A, Jepsen S, Kapferer-Seebacher I, Dommisch H, Berger K, Laudes M, Lieb W, Loos BG, van der Velde N, van Schoor N, de Groot L; PerioGEN Cohort Group; Blanco J, Carracedo A, Cruz R, Schaefer AS. De Almeida SD, et al. Among authors: schaefer as. J Clin Periodontol. 2024 Apr;51(4):431-440. doi: 10.1111/jcpe.13922. Epub 2023 Dec 23. J Clin Periodontol. 2024. PMID: 38140892
A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis.
Schaefer AS, Richter GM, Nothnagel M, Laine ML, Rühling A, Schäfer C, Cordes N, Noack B, Folwaczny M, Glas J, Dörfer C, Dommisch H, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S. Schaefer AS, et al. Genes Immun. 2010 Jan;11(1):45-54. doi: 10.1038/gene.2009.75. Epub 2009 Oct 15. Genes Immun. 2010. PMID: 19829306
COX-2 is associated with periodontitis in Europeans.
Schaefer AS, Richter GM, Nothnagel M, Laine ML, Noack B, Glas J, Schrezenmeir J, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S. Schaefer AS, et al. J Dent Res. 2010 Apr;89(4):384-8. doi: 10.1177/0022034509359575. Epub 2010 Feb 22. J Dent Res. 2010. PMID: 20177132
Common genetic risk variants of TLR2 are not associated with periodontitis in large European case-control populations.
Richter GM, Graetz C, Pohler P, Nothnagel M, Dommisch H, Laine ML, Folwaczny M, Noack B, Eickholz P, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S, Schaefer AS. Richter GM, et al. Among authors: schaefer as. J Clin Periodontol. 2012 Apr;39(4):315-22. doi: 10.1111/j.1600-051X.2011.01846.x. Epub 2012 Jan 18. J Clin Periodontol. 2012. PMID: 22251071
Validation of reported genetic risk factors for periodontitis in a large-scale replication study.
Schaefer AS, Bochenek G, Manke T, Nothnagel M, Graetz C, Thien A, Jockel-Schneider Y, Harks I, Staufenbiel I, Wijmenga C, Eberhard J, Guzeldemir-Akcakanat E, Cine N, Folwaczny M, Noack B, Meyle J, Eickholz P, Trombelli L, Scapoli C, Nohutcu R, Bruckmann C, Doerfer C, Jepsen S, Loos BG, Schreiber S. Schaefer AS, et al. J Clin Periodontol. 2013 Jun;40(6):563-72. doi: 10.1111/jcpe.12092. Epub 2013 Apr 16. J Clin Periodontol. 2013. PMID: 23587006
55 results