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Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration.
Jindal S, Pedersen DV, Gera N, Chandler J, Patel R, Neill A, Cone J, Zhang Y, Yuan CX, Millman EE, Carlin D, Puffer B, Sheridan D, Andersen GR, Tamburini P. Jindal S, et al. Among authors: puffer b. Mol Immunol. 2024 Jan;165:29-41. doi: 10.1016/j.molimm.2023.12.004. Epub 2023 Dec 23. Mol Immunol. 2024. PMID: 38142486 Free article.
Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices.
Wescott MP, Kufareva I, Paes C, Goodman JR, Thaker Y, Puffer BA, Berdougo E, Rucker JB, Handel TM, Doranz BJ. Wescott MP, et al. Among authors: puffer ba. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9928-33. doi: 10.1073/pnas.1601278113. Epub 2016 Aug 19. Proc Natl Acad Sci U S A. 2016. PMID: 27543332 Free PMC article.
Atomic-level functional model of dengue virus Envelope protein infectivity.
Christian EA, Kahle KM, Mattia K, Puffer BA, Pfaff JM, Miller A, Paes C, Davidson E, Doranz BJ. Christian EA, et al. Among authors: puffer ba. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18662-7. doi: 10.1073/pnas.1310962110. Epub 2013 Oct 24. Proc Natl Acad Sci U S A. 2013. PMID: 24158478 Free PMC article.
Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides.
LaFleur DW, Abramyan D, Kanakaraj P, Smith RG, Shah RR, Wang G, Yao XT, Kankanala S, Boyd E, Zaritskaya L, Nam V, Puffer BA, Buasen P, Kaithamana S, Burnette AF, Krishnamurthy R, Patel D, Roschke VV, Kiener PA, Hilbert DM, Barbas CF 3rd. LaFleur DW, et al. Among authors: puffer ba. MAbs. 2013 Mar-Apr;5(2):208-18. doi: 10.4161/mabs.23043. MAbs. 2013. PMID: 23575268 Free PMC article.
Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis.
Kanakaraj P, Puffer BA, Yao XT, Kankanala S, Boyd E, Shah RR, Wang G, Patel D, Krishnamurthy R, Kaithamana S, Smith RG, LaFleur DW, Barbas CF 3rd, Hilbert DM, Kiener PA, Roschke VV. Kanakaraj P, et al. Among authors: puffer ba. MAbs. 2012 Sep-Oct;4(5):600-13. doi: 10.4161/mabs.21227. Epub 2012 Aug 6. MAbs. 2012. PMID: 22864384 Free PMC article.
41 results