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Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational Burden.
Necchi A, Spiess PE, Costa de Padua T, Li R, Grivas P, Huang RSP, Lin DI, Danziger N, Ross JS, Jacob JM, Sager RA, Basnet A, Li G, Graf RP, Pavlick DC, Bratslavsky G. Necchi A, et al. Among authors: sager ra. JAMA Netw Open. 2023 Dec 1;6(12):e2348002. doi: 10.1001/jamanetworkopen.2023.48002. JAMA Netw Open. 2023. PMID: 38150257 Free PMC article.
Loss of Wave1 gene defines a subtype of lethal prostate cancer.
Sowalsky AG, Sager R, Schaefer RJ, Bratslavsky G, Pandolfi PP, Balk SP, Kotula L. Sowalsky AG, et al. Oncotarget. 2015 May 20;6(14):12383-91. doi: 10.18632/oncotarget.3564. Oncotarget. 2015. PMID: 25906751 Free PMC article.
Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer.
Dushukyan N, Dunn DM, Sager RA, Woodford MR, Loiselle DR, Daneshvar M, Baker-Williams AJ, Chisholm JD, Truman AW, Vaughan CK, Haystead TA, Bratslavsky G, Bourboulia D, Mollapour M. Dushukyan N, et al. Among authors: sager ra. Cell Rep. 2017 Nov 14;21(7):1883-1895. doi: 10.1016/j.celrep.2017.10.074. Cell Rep. 2017. PMID: 29141220 Free PMC article.
Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity.
Woodford MR, Hughes M, Sager RA, Backe SJ, Baker-Williams AJ, Bratslavsky MS, Jacob JM, Shapiro O, Wong M, Bratslavsky G, Bourboulia D, Mollapour M. Woodford MR, et al. Among authors: sager ra. Oncotarget. 2019 Oct 8;10(56):5824-5834. doi: 10.18632/oncotarget.27217. eCollection 2019 Oct 8. Oncotarget. 2019. PMID: 31645902 Free PMC article.
Fumarate hydratase as a therapeutic target in renal cancer.
Kancherla P, Daneshvar M, Sager RA, Mollapour M, Bratslavsky G. Kancherla P, et al. Among authors: sager ra. Expert Opin Ther Targets. 2020 Sep;24(9):923-936. doi: 10.1080/14728222.2020.1804862. Epub 2020 Oct 6. Expert Opin Ther Targets. 2020. PMID: 32744123 Review.
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect.
Woodford MR, Baker-Williams AJ, Sager RA, Backe SJ, Blanden AR, Hashmi F, Kancherla P, Gori A, Loiselle DR, Castelli M, Serapian SA, Colombo G, Haystead TA, Jensen SM, Stetler-Stevenson WG, Loh SN, Schmidt LS, Linehan WM, Bah A, Bourboulia D, Bratslavsky G, Mollapour M. Woodford MR, et al. Among authors: sager ra. Nat Struct Mol Biol. 2021 Aug;28(8):662-670. doi: 10.1038/s41594-021-00633-2. Epub 2021 Aug 11. Nat Struct Mol Biol. 2021. PMID: 34381247 Free PMC article.
Therapeutic potential of CDK4/6 inhibitors in renal cell carcinoma.
Sager RA, Backe SJ, Ahanin E, Smith G, Nsouli I, Woodford MR, Bratslavsky G, Bourboulia D, Mollapour M. Sager RA, et al. Nat Rev Urol. 2022 May;19(5):305-320. doi: 10.1038/s41585-022-00571-8. Epub 2022 Mar 9. Nat Rev Urol. 2022. PMID: 35264774 Free PMC article. Review.
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