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Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller.
Nat Commun. 2024 Jan 2;15(1):155. doi: 10.1038/s41467-023-44479-2.
Nat Commun. 2024.
PMID: 38168102
Free PMC article.
Myocilin misfolding and glaucoma: A 20-year update.
Saccuzzo EG, Youngblood HA, Lieberman RL.
Saccuzzo EG, et al.
Prog Retin Eye Res. 2023 Jul;95:101188. doi: 10.1016/j.preteyeres.2023.101188. Epub 2023 May 20.
Prog Retin Eye Res. 2023.
PMID: 37217093
Review.
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Calcium dysregulation potentiates wild-type myocilin misfolding: implications for glaucoma pathogenesis.
Saccuzzo EG, Martin MD, Hill KR, Ma MT, Ku Y, Lieberman RL.
Saccuzzo EG, et al.
J Biol Inorg Chem. 2022 Sep;27(6):553-564. doi: 10.1007/s00775-022-01946-3. Epub 2022 Jul 13.
J Biol Inorg Chem. 2022.
PMID: 35831671
Free PMC article.
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Common and rare myocilin variants: Predicting glaucoma pathogenicity based on genetics, clinical, and laboratory misfolding data.
Scelsi HF, Barlow BM, Saccuzzo EG, Lieberman RL.
Scelsi HF, et al. Among authors: saccuzzo eg.
Hum Mutat. 2021 Aug;42(8):903-946. doi: 10.1002/humu.24238. Epub 2021 Jun 24.
Hum Mutat. 2021.
PMID: 34082484
Free PMC article.
Review.
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Structural Arrangement within a Peptide Fibril Derived from the Glaucoma-Associated Myocilin Olfactomedin Domain.
Gao Y, Saccuzzo EG, Hill SE, Huard DJE, Robang AS, Lieberman RL, Paravastu AK.
Gao Y, et al. Among authors: saccuzzo eg.
J Phys Chem B. 2021 Mar 25;125(11):2886-2897. doi: 10.1021/acs.jpcb.0c11460. Epub 2021 Mar 8.
J Phys Chem B. 2021.
PMID: 33683890
Free PMC article.
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A blueprint for academic laboratories to produce SARS-CoV-2 quantitative RT-PCR test kits.
Mascuch SJ, Fakhretaha-Aval S, Bowman JC, Ma MTH, Thomas G, Bommarius B, Ito C, Zhao L, Newnam GP, Matange KR, Thapa HR, Barlow B, Donegan RK, Nguyen NA, Saccuzzo EG, Obianyor CT, Karunakaran SC, Pollet P, Rothschild-Mancinelli B, Mestre-Fos S, Guth-Metzler R, Bryksin AV, Petrov AS, Hazell M, Ibberson CB, Penev PI, Mannino RG, Lam WA, Garcia AJ, Kubanek J, Agarwal V, Hud NV, Glass JB, Williams LD, Lieberman RL.
Mascuch SJ, et al. Among authors: saccuzzo eg.
J Biol Chem. 2020 Nov 13;295(46):15438-15453. doi: 10.1074/jbc.RA120.015434. Epub 2020 Sep 3.
J Biol Chem. 2020.
PMID: 32883809
Free PMC article.
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A blueprint for academic labs to produce SARS-CoV-2 RT-qPCR test kits.
Mascuch SJ, Fakhretaha-Aval S, Bowman JC, Ma MTH, Thomas G, Bommarius B, Ito C, Zhao L, Newnam GP, Matange KR, Thapa HR, Barlow B, Donegan RK, Nguyen NA, Saccuzzo EG, Obianyor CT, Karunakaran SC, Pollet P, Rothschild-Mancinelli B, Mestre-Fos S, Guth-Metzler R, Bryksin AV, Petrov AS, Hazell M, Ibberson CB, Penev PI, Mannino RG, Lam WA, Garcia AJ, Kubanek JM, Agarwal V, Hud NV, Glass JB, Williams LD, Lieberman RL.
Mascuch SJ, et al. Among authors: saccuzzo eg.
medRxiv [Preprint]. 2020 Sep 1:2020.07.29.20163949. doi: 10.1101/2020.07.29.20163949.
medRxiv. 2020.
PMID: 32766604
Free PMC article.
Updated.
Preprint.
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