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Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection.
Zhang MJ, Durvasula A, Chiang C, Koch EM, Strober BJ, Shi H, Barton AR, Kim SS, Weissbrod O, Loh PR, Gazal S, Sunyaev S, Price AL. Zhang MJ, et al. Among authors: weissbrod o. medRxiv [Preprint]. 2023 Dec 4:2023.12.04.23299391. doi: 10.1101/2023.12.04.23299391. medRxiv. 2023. PMID: 38106023 Free PMC article. Preprint.
Improving fine-mapping by modeling infinitesimal effects.
Cui R, Elzur RA, Kanai M, Ulirsch JC, Weissbrod O, Daly MJ, Neale BM, Fan Z, Finucane HK. Cui R, et al. Among authors: weissbrod o. Nat Genet. 2024 Jan;56(1):162-169. doi: 10.1038/s41588-023-01597-3. Epub 2023 Nov 30. Nat Genet. 2024. PMID: 38036779 Free PMC article.
Bacterial SNPs in the human gut microbiome associate with host BMI.
Zahavi L, Lavon A, Reicher L, Shoer S, Godneva A, Leviatan S, Rein M, Weissbrod O, Weinberger A, Segal E. Zahavi L, et al. Among authors: weissbrod o. Nat Med. 2023 Nov;29(11):2785-2792. doi: 10.1038/s41591-023-02599-8. Epub 2023 Nov 2. Nat Med. 2023. PMID: 37919437 Free PMC article.
From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis.
Yogev O, Weissbrod O, Battistoni G, Bressan D, Naamati A, Falciatori I, Berkyurek AC, Rasnic R, Izuagbe R, Hosmillo M, Ilan S, Grossman I, McCormick L, Honeycutt CC, Johnston T, Gagne M, Douek DC, Goodfellow I, Hannon GJ, Erlich Y. Yogev O, et al. Among authors: weissbrod o. Commun Biol. 2023 Mar 16;6(1):277. doi: 10.1038/s42003-023-04589-5. Commun Biol. 2023. PMID: 36928598 Free PMC article.
Open problems in human trait genetics.
Brandes N, Weissbrod O, Linial M. Brandes N, et al. Among authors: weissbrod o. Genome Biol. 2022 Jun 20;23(1):131. doi: 10.1186/s13059-022-02697-9. Genome Biol. 2022. PMID: 35725481 Free PMC article. Review.
Genome wide screen of RNAi molecules against SARS-CoV-2 creates a broadly potent prophylaxis.
Yogev O, Weissbrod O, Battistoni G, Bressan D, Naamti A, Falciatori I, Berkyurek AC, Rasnic R, Hosmillo M, Ilan S, Grossman I, McCormick L, Honeycutt CC, Johnston T, Gagne M, Douek DC, Goodfellow I, Hannon GJ, Erlich Y. Yogev O, et al. Among authors: weissbrod o. bioRxiv [Preprint]. 2022 Apr 12:2022.04.12.488010. doi: 10.1101/2022.04.12.488010. bioRxiv. 2022. PMID: 35441162 Free PMC article. Updated. Preprint.
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS.
Eitan C, Siany A, Barkan E, Olender T, van Eijk KR, Moisse M, Farhan SMK, Danino YM, Yanowski E, Marmor-Kollet H, Rivkin N, Yacovzada NS, Hung ST, Cooper-Knock J, Yu CH, Louis C, Masters SL, Kenna KP, van der Spek RAA, Sproviero W, Al Khleifat A, Iacoangeli A, Shatunov A, Jones AR, Elbaz-Alon Y, Cohen Y, Chapnik E, Rothschild D, Weissbrod O, Beck G, Ainbinder E, Ben-Dor S, Werneburg S, Schafer DP, Brown RH Jr, Shaw PJ, Van Damme P, van den Berg LH, Phatnani H, Segal E, Ichida JK, Al-Chalabi A, Veldink JH; Project MinE ALS Sequencing Consortium; NYGC ALS Consortium; Hornstein E. Eitan C, et al. Among authors: weissbrod o. Nat Neurosci. 2022 Apr;25(4):433-445. doi: 10.1038/s41593-022-01040-6. Epub 2022 Mar 31. Nat Neurosci. 2022. PMID: 35361972 Free PMC article.
41 results