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Page 1
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology.
Mancuso R, Fattorelli N, Martinez-Muriana A, Davis E, Wolfs L, Van Den Daele J, Geric I, Premereur J, Polanco P, Bijnens B, Preman P, Serneels L, Poovathingal S, Balusu S, Verfaillie C, Fiers M, De Strooper B. Mancuso R, et al. Among authors: balusu s. Nat Neurosci. 2024 May;27(5):886-900. doi: 10.1038/s41593-024-01600-y. Epub 2024 Mar 27. Nat Neurosci. 2024. PMID: 38539015 Free PMC article.
Evaluation of FluSight influenza forecasting in the 2021-22 and 2022-23 seasons with a new target laboratory-confirmed influenza hospitalizations.
Mathis SM, Webber AE, León TM, Murray EL, Sun M, White LA, Brooks LC, Green A, Hu AJ, McDonald DJ, Rosenfeld R, Shemetov D, Tibshirani RJ, Kandula S, Pei S, Shaman J, Yaari R, Yamana TK, Agarwal P, Balusu S, Gururajan G, Kamarthi H, Prakash BA, Raman R, Rodríguez A, Zhao Z, Meiyappan A, Omar S, Baccam P, Gurung HL, Stage SA, Suchoski BT, Ajelli M, Kummer AG, Litvinova M, Ventura PC, Wadsworth S, Niemi J, Carcelen E, Hill AL, Jung SM, Lemaitre JC, Lessler J, Loo SL, McKee CD, Sato K, Smith C, Truelove S, McAndrew T, Ye W, Bosse N, Hlavacek WS, Lin YT, Mallela A, Chen Y, Lamm SM, Lee J, Posner RG, Perofsky AC, Viboud C, Clemente L, Lu F, Meyer AG, Santillana M, Chinazzi M, Davis JT, Mu K, Piontti APY, Vespignani A, Xiong X, Ben-Nun M, Riley P, Turtle J, Hulme-Lowe C, Jessa S, Nagraj VP, Turner SD, Williams D, Basu A, Drake JM, Fox SJ, Gibson GC, Suez E, Thommes EW, Cojocaru MG, Cramer EY, Gerding A, Stark A, Ray EL, Reich NG, Shandross L, Wattanachit N, Wang Y, Zorn MW, Al Aawar M, Srivastava A, Meyers LA, Adiga A, Hurt B, Kaur G, Lewis BL, Marathe M, Venkatramanan S, Butler P, Farabow A, Muralidhar N, Ramakrishnan N, Reed C, Biggerstaff M, Borchering RK. Mathis SM, et al. Among authors: balusu s. medRxiv [Preprint]. 2023 Dec 11:2023.12.08.23299726. doi: 10.1101/2023.12.08.23299726. medRxiv. 2023. PMID: 38168429 Free PMC article. Preprint.
The γ-secretase substrate proteome and its role in cell signaling regulation.
Hou P, Zielonka M, Serneels L, Martinez-Muriana A, Fattorelli N, Wolfs L, Poovathingal S, T'Syen D, Balusu S, Theys T, Fiers M, Mancuso R, Howden AJM, De Strooper B. Hou P, et al. Among authors: balusu s. Mol Cell. 2023 Nov 16;83(22):4106-4122.e10. doi: 10.1016/j.molcel.2023.10.029. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977120 Free article.
MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
Balusu S, Horré K, Thrupp N, Craessaerts K, Snellinx A, Serneels L, T'Syen D, Chrysidou I, Arranz AM, Sierksma A, Simrén J, Karikari TK, Zetterberg H, Chen WT, Thal DR, Salta E, Fiers M, De Strooper B. Balusu S, et al. Science. 2023 Sep 15;381(6663):1176-1182. doi: 10.1126/science.abp9556. Epub 2023 Sep 14. Science. 2023. PMID: 37708272 Free PMC article.
Neurodegeneration cell per cell.
Balusu S, Praschberger R, Lauwers E, De Strooper B, Verstreken P. Balusu S, et al. Neuron. 2023 Mar 15;111(6):767-786. doi: 10.1016/j.neuron.2023.01.016. Epub 2023 Feb 13. Neuron. 2023. PMID: 36787752 Free article. Review.
Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics.
Pauwels MJ, Xie J, Ceroi A, Balusu S, Castelein J, Van Wonterghem E, Van Imschoot G, Ward A, Menheniott TR, Gustafsson O, Combes F, El Andaloussi S, Sanders NN, Mäger I, Van Hoecke L, Vandenbroucke RE. Pauwels MJ, et al. Among authors: balusu s. Biomaterials. 2022 Nov;290:121830. doi: 10.1016/j.biomaterials.2022.121830. Epub 2022 Oct 6. Biomaterials. 2022. PMID: 36302306
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease.
Koper MJ, Tomé SO, Gawor K, Belet A, Van Schoor E, Schaeverbeke J, Vandenberghe R, Vandenbulcke M, Ghebremedhin E, Otto M, von Arnim CAF, Balusu S, Blaschko MB, De Strooper B, Thal DR. Koper MJ, et al. Among authors: balusu s. Acta Neuropathol Commun. 2022 Sep 3;10(1):128. doi: 10.1186/s40478-022-01432-6. Acta Neuropathol Commun. 2022. PMID: 36057624 Free PMC article.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Guo W, Wang H, Kumar Tharkeshwar A, Couthouis J, Braems E, Masrori P, Van Schoor E, Fan Y, Ahuja K, Moisse M, Jacquemyn M, Furtado Madeiro da Costa R, Gajjar M, Balusu S, Tricot T, Fumagalli L, Hersmus N, Janky R, Impens F, Vanden Berghe P, Ho R, Thal DR, Vandenberghe R, Hegde ML, Chandran S, De Strooper B, Daelemans D, Van Damme P, Van Den Bosch L, Verfaillie C. Guo W, et al. Among authors: balusu s. Alzheimers Dement. 2023 Apr;19(4):1245-1259. doi: 10.1002/alz.12760. Epub 2022 Aug 22. Alzheimers Dement. 2023. PMID: 35993441 Free PMC article.
Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles.
Gupta D, Wiklander OPB, Görgens A, Conceição M, Corso G, Liang X, Seow Y, Balusu S, Feldin U, Bostancioglu B, Jawad R, Mamand DR, Lee YXF, Hean J, Mäger I, Roberts TC, Gustafsson M, Mohammad DK, Sork H, Backlund A, Lundin P, de Fougerolles A, Smith CIE, Wood MJA, Vandenbroucke RE, Nordin JZ, El-Andaloussi S. Gupta D, et al. Among authors: balusu s. Nat Biomed Eng. 2021 Sep;5(9):1084-1098. doi: 10.1038/s41551-021-00792-z. Epub 2021 Oct 6. Nat Biomed Eng. 2021. PMID: 34616047
Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease.
Vandendriessche C, Balusu S, Van Cauwenberghe C, Brkic M, Pauwels M, Plehiers N, Bruggeman A, Dujardin P, Van Imschoot G, Van Wonterghem E, Hendrix A, Baeke F, De Rycke R, Gevaert K, Vandenbroucke RE. Vandendriessche C, et al. Among authors: balusu s. Acta Neuropathol Commun. 2021 Aug 23;9(1):143. doi: 10.1186/s40478-021-01245-z. Acta Neuropathol Commun. 2021. PMID: 34425919 Free PMC article.
32 results