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HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence.
Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S. Cui M, et al. Among authors: yamamoto k, yamamoto imoto h, yamamoto t. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306454120. doi: 10.1073/pnas.2306454120. Epub 2024 Jan 3. Proc Natl Acad Sci U S A. 2024. PMID: 38170752
Autophagy Inhibits the Accumulation of Advanced Glycation End Products by Promoting Lysosomal Biogenesis and Function in the Kidney Proximal Tubules.
Takahashi A, Takabatake Y, Kimura T, Maejima I, Namba T, Yamamoto T, Matsuda J, Minami S, Kaimori JY, Matsui I, Matsusaka T, Niimura F, Yoshimori T, Isaka Y. Takahashi A, et al. Among authors: yamamoto t. Diabetes. 2017 May;66(5):1359-1372. doi: 10.2337/db16-0397. Epub 2017 Feb 28. Diabetes. 2017. PMID: 28246295
Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation.
Minami S, Yamamoto T, Takabatake Y, Takahashi A, Namba T, Matsuda J, Kimura T, Kaimori JY, Matsui I, Hamano T, Takeda H, Takahashi M, Izumi Y, Bamba T, Matsusaka T, Niimura F, Isaka Y. Minami S, et al. Among authors: yamamoto t. Autophagy. 2017 Oct 3;13(10):1629-1647. doi: 10.1080/15548627.2017.1341464. Epub 2017 Aug 16. Autophagy. 2017. PMID: 28813167 Free PMC article.
Antioxidant role of autophagy in maintaining the integrity of glomerular capillaries.
Matsuda J, Namba T, Takabatake Y, Kimura T, Takahashi A, Yamamoto T, Minami S, Sakai S, Fujimura R, Kaimori JY, Matsui I, Hamano T, Fukushima Y, Matsui K, Soga T, Isaka Y. Matsuda J, et al. Among authors: yamamoto t. Autophagy. 2018;14(1):53-65. doi: 10.1080/15548627.2017.1391428. Autophagy. 2018. PMID: 29130363 Free PMC article.
Proximal Tubule Autophagy Differs in Type 1 and 2 Diabetes.
Sakai S, Yamamoto T, Takabatake Y, Takahashi A, Namba-Hamano T, Minami S, Fujimura R, Yonishi H, Matsuda J, Hesaka A, Matsui I, Matsusaka T, Niimura F, Yanagita M, Isaka Y. Sakai S, et al. Among authors: yamamoto t. J Am Soc Nephrol. 2019 Jun;30(6):929-945. doi: 10.1681/ASN.2018100983. Epub 2019 Apr 30. J Am Soc Nephrol. 2019. PMID: 31040190 Free PMC article.
Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.
Matsuda J, Takahashi A, Takabatake Y, Sakai S, Minami S, Yamamoto T, Fujimura R, Namba-Hamano T, Yonishi H, Nakamura J, Kimura T, Kaimori JY, Matsui I, Takahashi M, Nakao M, Izumi Y, Bamba T, Matsusaka T, Niimura F, Yanagita M, Yoshimori T, Isaka Y. Matsuda J, et al. Among authors: yamamoto t. Autophagy. 2020 Oct;16(10):1889-1904. doi: 10.1080/15548627.2020.1712107. Epub 2020 Jan 16. Autophagy. 2020. PMID: 31944172 Free PMC article.
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