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Page 1
Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils.
Patterson JR, Kochmanski J, Stoll AC, Kubik M, Kemp CJ, Duffy MF, Thompson K, Howe JW, Cole-Strauss A, Kuhn NC, Miller KM, Nelson S, Onyekpe CU, Beck JS, Counts SE, Bernstein AI, Steece-Collier K, Luk KC, Sortwell CE. Patterson JR, et al. NPJ Parkinsons Dis. 2024 Jan 3;10(1):7. doi: 10.1038/s41531-023-00620-y. NPJ Parkinsons Dis. 2024. PMID: 38172128 Free PMC article.
Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.
Manfredsson FP, Luk KC, Benskey MJ, Gezer A, Garcia J, Kuhn NC, Sandoval IM, Patterson JR, O'Mara A, Yonkers R, Kordower JH. Manfredsson FP, et al. Among authors: patterson jr. Neurobiol Dis. 2018 Apr;112:106-118. doi: 10.1016/j.nbd.2018.01.008. Epub 2018 Jan 16. Neurobiol Dis. 2018. PMID: 29341898 Free PMC article.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
Duffy MF, Collier TJ, Patterson JR, Kemp CJ, Luk KC, Tansey MG, Paumier KL, Kanaan NM, Fischer DL, Polinski NK, Barth OL, Howe JW, Vaikath NN, Majbour NK, El-Agnaf OMA, Sortwell CE. Duffy MF, et al. Among authors: patterson jr. J Neuroinflammation. 2018 May 1;15(1):129. doi: 10.1186/s12974-018-1171-z. J Neuroinflammation. 2018. PMID: 29716614 Free PMC article.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
Duffy MF, Collier TJ, Patterson JR, Kemp CJ, Luk KC, Tansey MG, Paumier KL, Kanaan NM, Fischer DL, Polinski NK, Barth OL, Howe JW, Vaikath NN, Majbour NK, El-Agnaf OMA, Sortwell CE. Duffy MF, et al. Among authors: patterson jr. J Neuroinflammation. 2018 May 29;15(1):169. doi: 10.1186/s12974-018-1202-9. J Neuroinflammation. 2018. PMID: 29843738 Free PMC article.
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Patterson JR, Duffy MF, Kemp CJ, Howe JW, Collier TJ, Stoll AC, Miller KM, Patel P, Levine N, Moore DJ, Luk KC, Fleming SM, Kanaan NM, Paumier KL, El-Agnaf OMA, Sortwell CE. Patterson JR, et al. Neurobiol Dis. 2019 Oct;130:104525. doi: 10.1016/j.nbd.2019.104525. Epub 2019 Jul 2. Neurobiol Dis. 2019. PMID: 31276792 Free PMC article.
Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits.
Gezer AO, Kochmanski J, VanOeveren SE, Cole-Strauss A, Kemp CJ, Patterson JR, Miller KM, Kuhn NC, Herman DE, McIntire A, Lipton JW, Luk KC, Fleming SM, Sortwell CE, Bernstein AI. Gezer AO, et al. Among authors: patterson jr. Neurobiol Dis. 2020 Jul;141:104947. doi: 10.1016/j.nbd.2020.104947. Epub 2020 May 15. Neurobiol Dis. 2020. PMID: 32422283 Free PMC article.
Striatal Afferent BDNF Is Disrupted by Synucleinopathy and Partially Restored by STN DBS.
Miller KM, Patterson JR, Kochmanski J, Kemp CJ, Stoll AC, Onyekpe CU, Cole-Strauss A, Steece-Collier K, Howe JW, Luk KC, Sortwell CE. Miller KM, et al. Among authors: patterson jr. J Neurosci. 2021 Mar 3;41(9):2039-2052. doi: 10.1523/JNEUROSCI.1952-20.2020. Epub 2021 Jan 20. J Neurosci. 2021. PMID: 33472823 Free PMC article.
943 results