Sawaya M - Search Results

1

X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation.

Agdanowski MP, Castells-Graells R, Sawaya MR, Cascio D, Yeates TO, Arbing MA. Agdanowski MP, et al. Among authors: sawaya mr. Acta Crystallogr F Struct Biol Commun. 2024 May 1. doi: 10.1107/S2053230X2400414X. Online ahead of print. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 38767964

2

How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.

Eisenberg D, Hou K, Ge P, Sawaya M, Dolinsky J, Yang Y, Jiang YX, Lutter L, Boyer D, Cheng X, Pi J, Zhang J, Lu J, Yang S, Yu Z, Feigon J. Eisenberg D, et al. Among authors: sawaya m. Res Sq [Preprint]. 2024 May 8:rs.3.rs-4152095. doi: 10.21203/rs.3.rs-4152095/v1. Res Sq. 2024. PMID: 38766197 Free PMC article. Preprint.

3

D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease.

Hou K, Pan H, Shahpasand-Kroner H, Hu C, Abskharon R, Seidler P, Mekkittikul M, Balbirnie M, Lantz C, Sawaya MR, Dolinsky JL, Jones M, Zuo X, Loo JA, Frautschy S, Cole G, Eisenberg DS. Hou K, et al. Among authors: sawaya mr. Sci Adv. 2024 May 3;10(18):eadl2991. doi: 10.1126/sciadv.adl2991. Epub 2024 May 1. Sci Adv. 2024. PMID: 38691615 Free PMC article.

4

How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.

Hou K, Ge P, Sawaya MR, Dolinsky JL, Yang Y, Jiang YX, Lutter L, Boyer DR, Cheng X, Pi J, Zhang J, Lu J, Yang S, Yu Z, Feigon J, Eisenberg DS. Hou K, et al. Among authors: sawaya mr. bioRxiv [Preprint]. 2024 Mar 29:2024.03.25.586668. doi: 10.1101/2024.03.25.586668. bioRxiv. 2024. PMID: 38585812 Free PMC article. Preprint.

5

A suite of designed protein cages using machine learning and protein fragment-based protocols.

Meador K, Castells-Graells R, Aguirre R, Sawaya MR, Arbing MA, Sherman T, Senarathne C, Yeates TO. Meador K, et al. Among authors: sawaya mr. Structure. 2024 Mar 19:S0969-2126(24)00056-X. doi: 10.1016/j.str.2024.02.017. Online ahead of print. Structure. 2024. PMID: 38513658 Free article.

6

DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity.

Ryder BD, Ustyantseva E, Boyer DR, Mendoza-Oliva A, Kuska MI, Wydorski PM, Macierzyńska P, Morgan N, Sawaya MR, Diamond MI, Kampinga HH, Joachimiak LA. Ryder BD, et al. Among authors: sawaya mr. Structure. 2024 Mar 8:S0969-2126(24)00055-8. doi: 10.1016/j.str.2024.02.015. Online ahead of print. Structure. 2024. PMID: 38508190

7

AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography.

Miller JE, Agdanowski MP, Dolinsky JL, Sawaya MR, Cascio D, Rodriguez JA, Yeates TO. Miller JE, et al. Among authors: sawaya mr. Acta Crystallogr D Struct Biol. 2024 Apr 1;80(Pt 4):270-278. doi: 10.1107/S205979832400072X. Epub 2024 Mar 7. Acta Crystallogr D Struct Biol. 2024. PMID: 38451205 Free PMC article.

8

Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.

Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pękała M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L. Nguyen BA, et al. Among authors: sawaya mr. Nat Commun. 2024 Jan 17;15(1):581. doi: 10.1038/s41467-024-44820-3. Nat Commun. 2024. PMID: 38233397 Free PMC article.

9

Sexually and non-sexually transmitted infections and the risk of prostate cancer: Results from the EPICAP study.

Sawaya M, Cordina-Duverger E, Lamy PJ, Rébillard X, Trétarre B, Menegaux F. Sawaya M, et al. Cancer Med. 2024 Jan 4;13(1):e6841. doi: 10.1002/cam4.6841. Online ahead of print. Cancer Med. 2024. PMID: 38174802 Free PMC article.

10

Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method.

Rosenberg GM, Abskharon R, Boyer DR, Ge P, Sawaya MR, Eisenberg DS. Rosenberg GM, et al. Among authors: sawaya mr. PNAS Nexus. 2023 Nov 20;2(12):pgad402. doi: 10.1093/pnasnexus/pgad402. eCollection 2023 Dec. PNAS Nexus. 2023. PMID: 38077690 Free PMC article.

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