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Page 1
Multiomic foundations of human prefrontal cortex tissue function.
Kopell BH, Kaji DA, Liharska LE, Vornholt E, Valentine A, Lund A, Hashemi A, Thompson RC, Lohrenz T, Johnson JS, Bussola N, Cheng E, Park YJ, Shah P, Ma W, Searfoss R, Qasim S, Miller GM, Chand NM, Aristel A, Humphrey J, Wilkins L, Ziafat K, Silk H, Linares LM, Sullivan B, Feng C, Batten SR, Bang D, Barbosa LS, Twomey T, White JP, Vannucci M, Hadj-Amar B, Cohen V, Kota P, Moya E, Rieder MK, Figee M, Nadkarni GN, Breen MS, Kishida KT, Scarpa J, Ruderfer DM, Narain NR, Wang P, Kiebish MA, Schadt EE, Saez I, Montague PR, Beckmann ND, Charney AW. Kopell BH, et al. Among authors: breen ms. medRxiv [Preprint]. 2024 May 17:2024.05.17.24307537. doi: 10.1101/2024.05.17.24307537. medRxiv. 2024. PMID: 38798344 Free PMC article. Preprint.
Divergent landscapes of A-to-I editing in postmortem and living human brain.
de Los Santos MR, Kopell BH, Grice AB, Ganesh G, Yang A, Amini P, Liharska LE, Vornholt E, Fullard JF, Dong P, Park E, Zipkowitz S, Kaji DA, Thompson RC, Liu D, Park YJ, Cheng E, Ziafat K, Moya E, Fennessy B, Wilkins L, Silk H, Linares LM, Sullivan B, Cohen V, Kota P, Feng C, Johnson JS, Rieder MK, Scarpa J, Nadkarni GN, Wang M, Zhang B, Sklar P, Beckmann ND, Schadt EE, Roussos P, Charney AW, Breen MS. de Los Santos MR, et al. Among authors: breen ms. medRxiv [Preprint]. 2024 May 9:2024.05.06.24306763. doi: 10.1101/2024.05.06.24306763. medRxiv. 2024. PMID: 38765961 Free PMC article. Preprint.
A primer on the use of machine learning to distil knowledge from data in biological psychiatry.
Quinn TP, Hess JL, Marshe VS, Barnett MM, Hauschild AC, Maciukiewicz M, Elsheikh SSM, Men X, Schwarz E, Trakadis YJ, Breen MS, Barnett EJ, Zhang-James Y, Ahsen ME, Cao H, Chen J, Hou J, Salekin A, Lin PI, Nicodemus KK, Meyer-Lindenberg A, Bichindaritz I, Faraone SV, Cairns MJ, Pandey G, Müller DJ, Glatt SJ; Machine Learning in Psychiatry (MLPsych) Consortium. Quinn TP, et al. Among authors: breen ms. Mol Psychiatry. 2024 Feb;29(2):387-401. doi: 10.1038/s41380-023-02334-2. Epub 2024 Jan 4. Mol Psychiatry. 2024. PMID: 38177352 Review.
Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice.
Osman A, Mervosh NL, Strat AN, Euston TJ, Zipursky G, Pollak RM, Meckel KR, Tyler SR, Chan KL, Buxbaum Grice A, Drapeau E, Litichevskiy L, Gill J, Zeldin SM, Thaiss CA, Buxbaum JD, Breen MS, Kiraly DD. Osman A, et al. Among authors: breen ms. Brain Behav Immun. 2023 Nov;114:311-324. doi: 10.1016/j.bbi.2023.08.020. Epub 2023 Aug 30. Brain Behav Immun. 2023. PMID: 37657643
Spatiotemporal and genetic regulation of A-to-I editing throughout human brain development.
Cuddleston WH, Fan X, Sloofman L, Liang L, Mossotto E, Moore K, Zipkowitz S, Wang M, Zhang B, Wang J, Sestan N, Devlin B, Roeder K, Sanders SJ, Buxbaum JD, Breen MS. Cuddleston WH, et al. Among authors: breen ms. Cell Rep. 2022 Nov 1;41(5):111585. doi: 10.1016/j.celrep.2022.111585. Cell Rep. 2022. PMID: 36323256 Free PMC article.
Large 22q13.3 deletions perturb peripheral transcriptomic and metabolomic profiles in Phelan-McDermid syndrome.
Breen MS, Fan X, Levy T, Pollak RM, Collins B, Osman A, Tocheva AS, Sahin M, Berry-Kravis E, Soorya L, Thurm A, Powell CM, Bernstein JA, Kolevzon A, Buxbaum JD; Developmental Synaptopathies Consortium. Breen MS, et al. HGG Adv. 2022 Sep 26;4(1):100145. doi: 10.1016/j.xhgg.2022.100145. eCollection 2023 Jan 12. HGG Adv. 2022. PMID: 36276299 Free PMC article.
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression.
Seah C, Breen MS, Rusielewicz T, Bader HN, Xu C, Hunter CJ, McCarthy B, Deans PJM, Chattopadhyay M, Goldberg J, Desarnaud F, Makotkine I, Flory JD, Bierer LM, Staniskyte M; NYSCF Global Stem Cell Array® Team; Noggle SA, Huckins LM, Paull D, Brennand KJ, Yehuda R. Seah C, et al. Among authors: breen ms. Nat Neurosci. 2022 Nov;25(11):1434-1445. doi: 10.1038/s41593-022-01161-y. Epub 2022 Oct 20. Nat Neurosci. 2022. PMID: 36266471 Free PMC article.
73 results