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IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development.
Goh W, Sudholz H, Foroutan M, Scheer S, Pfefferle A, Delconte RB, Meng X, Shen Z, Hennessey R, Kong IY, Schuster IS, Andoniou CE, Davis MJ, Hediyeh-Zadeh S, Souza-Fonseca-Guimaraes F, Parish IA, Beavis P, Thiele D, Chopin M, Degli-Esposti MA, Cursons J, Kallies A, Rautela J, Nutt SL, Huntington ND. Goh W, et al. Nat Immunol. 2024 Feb;25(2):240-255. doi: 10.1038/s41590-023-01718-4. Epub 2024 Jan 5. Nat Immunol. 2024. PMID: 38182668
Regulation of Murine Natural Killer Cell Development.
Goh W, Huntington ND. Goh W, et al. Front Immunol. 2017 Feb 15;8:130. doi: 10.3389/fimmu.2017.00130. eCollection 2017. Front Immunol. 2017. PMID: 28261203 Free PMC article. Review.
NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS.
Delconte RB, Guittard G, Goh W, Hediyeh-Zadeh S, Hennessy RJ, Rautela J, Davis MJ, Souza-Fonseca-Guimaraes F, Nunès JA, Huntington ND. Delconte RB, et al. Among authors: goh w. Front Immunol. 2020 Jan 31;11:75. doi: 10.3389/fimmu.2020.00075. eCollection 2020. Front Immunol. 2020. PMID: 32082327 Free PMC article.
Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells.
Rautela J, Dagley LF, Kratina T, Anthony A, Goh W, Surgenor E, Delconte RB, Webb AI, Elwood N, Groom JR, Souza-Fonseca-Guimaraes F, Corcoran L, Huntington ND. Rautela J, et al. Among authors: goh w. Mol Immunol. 2019 Nov;115:56-63. doi: 10.1016/j.molimm.2018.08.017. Epub 2018 Aug 23. Mol Immunol. 2019. PMID: 30144957
CD45 limits early Natural Killer cell development.
Meza Guzman LG, Hyland CD, Bidgood GM, Leong E, Shen Z, Goh W, Rautela J, Vince JE, Nicholson SE, Huntington ND. Meza Guzman LG, et al. Among authors: goh w. Immunol Cell Biol. 2024 Jan;102(1):58-70. doi: 10.1111/imcb.12701. Epub 2023 Oct 19. Immunol Cell Biol. 2024. PMID: 37855066 Free PMC article.
Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes.
Jiao Y, Davis JE, Rautela J, Carrington EM, Ludford-Menting MJ, Goh W, Delconte RB, Souza-Fonseca-Guimaraes F, Koldej R, Gray D, Huang D, Kile BT, Lew AM, Ritchie DS, Huntington ND. Jiao Y, et al. Among authors: goh w. Cell Death Differ. 2019 Aug;26(8):1516-1530. doi: 10.1038/s41418-018-0228-y. Epub 2018 Nov 12. Cell Death Differ. 2019. PMID: 30420758 Free PMC article.
Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival.
Viant C, Guia S, Hennessy RJ, Rautela J, Pham K, Bernat C, Goh W, Jiao Y, Delconte R, Roger M, Simon V, Souza-Fonseca-Guimaraes F, Grabow S, Belz GT, Kile BT, Strasser A, Gray D, Hodgkin PD, Beutler B, Vivier E, Ugolini S, Huntington ND. Viant C, et al. Among authors: goh w. J Exp Med. 2017 Feb;214(2):491-510. doi: 10.1084/jem.20160869. Epub 2017 Jan 5. J Exp Med. 2017. PMID: 28057804 Free PMC article.
Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer.
Williams MJ, Oliphant MU, Au V, Liu C, Baril C, O'Flanagan C, Lai D, Beatty S, Van Vliet M, Yiu JC, O'Connor L, Goh WL, Pollaci A, Weiner AC, Grewal D, McPherson A, Moore M, Prabhakar V, Agarwal S, Garber JE, Dillon D, Shah SP, Brugge J, Aparicio S. Williams MJ, et al. Among authors: goh wl. bioRxiv [Preprint]. 2024 May 3:2024.05.01.591587. doi: 10.1101/2024.05.01.591587. bioRxiv. 2024. PMID: 38746396 Free PMC article. Preprint.
397 results