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IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development.
Goh W, Sudholz H, Foroutan M, Scheer S, Pfefferle A, Delconte RB, Meng X, Shen Z, Hennessey R, Kong IY, Schuster IS, Andoniou CE, Davis MJ, Hediyeh-Zadeh S, Souza-Fonseca-Guimaraes F, Parish IA, Beavis P, Thiele D, Chopin M, Degli-Esposti MA, Cursons J, Kallies A, Rautela J, Nutt SL, Huntington ND. Goh W, et al. Among authors: pfefferle a. Nat Immunol. 2024 Feb;25(2):240-255. doi: 10.1038/s41590-023-01718-4. Epub 2024 Jan 5. Nat Immunol. 2024. PMID: 38182668
Optimisation of a primary human CAR-NK cell manufacturing pipeline.
Pfefferle A, Contet J, Wong K, Chen C, Verhoeyen E, Slichter CK, Schluns KS, Cursons J, Berry R, Nikolic I, Rautela J, Huntington ND. Pfefferle A, et al. Clin Transl Immunology. 2024 May 2;13(5):e1507. doi: 10.1002/cti2.1507. eCollection 2024. Clin Transl Immunology. 2024. PMID: 38707997 Free PMC article.
Remodeling of secretory lysosomes during education tunes functional potential in NK cells.
Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ. Goodridge JP, et al. Among authors: pfefferle a. Nat Commun. 2019 Jan 31;10(1):514. doi: 10.1038/s41467-019-08384-x. Nat Commun. 2019. PMID: 30705279 Free PMC article.
Deciphering Natural Killer Cell Homeostasis.
Pfefferle A, Jacobs B, Haroun-Izquierdo A, Kveberg L, Sohlberg E, Malmberg KJ. Pfefferle A, et al. Front Immunol. 2020 May 12;11:812. doi: 10.3389/fimmu.2020.00812. eCollection 2020. Front Immunol. 2020. PMID: 32477340 Free PMC article. Review.
Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia.
Sohlberg E, Pfefferle A, Heggernes Ask E, Tschan-Plessl A, Jacobs B, Netskar H, Lorenz S, Kanaya M, Kosugi-Kanaya M, Meinke S, Mörtberg A, Höglund P, Sundin M, Carlsson G, Palmblad J, Malmberg KJ. Sohlberg E, et al. Among authors: pfefferle a. Blood. 2022 Feb 3;139(5):704-716. doi: 10.1182/blood.2021013233. Blood. 2022. PMID: 34699594 Free article.
43 results