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E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE-/- mouse model.
Reumann MK, Schaefer J, Titz B, Aspera-Werz RH, Wong ET, Szostak J, Häussling V, Ehnert S, Leroy P, Tan WT, Kuczaj A, Audretsch C, Springer F, Badke A, Augat P, Quentanilla-Fend L, Martella M, Lee KM, Peitsch MC, Hoeng J, Nussler AK. Reumann MK, et al. Among authors: szostak j. Arch Toxicol. 2020 Jun;94(6):2163-2177. doi: 10.1007/s00204-020-02769-4. Epub 2020 May 14. Arch Toxicol. 2020. PMID: 32409933 Free PMC article.
Ceramide ratios are affected by cigarette smoke but not heat-not-burn or e-vapor aerosols across four independent mouse studies.
Lavrynenko O, Titz B, Dijon S, Santos DD, Nury C, Schneider T, Guedj E, Szostak J, Kondylis A, Phillips B, Ekroos K, Martin F, Peitsch MC, Hoeng J, Ivanov NV. Lavrynenko O, et al. Among authors: szostak j. Life Sci. 2020 Dec 15;263:118753. doi: 10.1016/j.lfs.2020.118753. Epub 2020 Nov 12. Life Sci. 2020. PMID: 33189821 Free article.
Impact of whole-body versus nose-only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2-month cigarette smoke exposure study in the ApoE-/- mouse model.
Kogel U, Wong ET, Szostak J, Tan WT, Lucci F, Leroy P, Titz B, Xiang Y, Low T, Wong SK, Guedj E, Ivanov NV, Schlage WK, Peitsch MC, Kuczaj A, Vanscheeuwijck P, Hoeng J. Kogel U, et al. Among authors: szostak j. J Appl Toxicol. 2021 Oct;41(10):1598-1619. doi: 10.1002/jat.4149. Epub 2021 Apr 6. J Appl Toxicol. 2021. PMID: 33825214 Free PMC article.
A 6-month inhalation toxicology study in Apoe-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Wong ET, Szostak J, Titz B, Lee T, Wong SK, Lavrynenko O, Merg C, Corciulo M, Simicevic J, Auberson M, Peric D, Dulize R, Bornand D, Loh GJ, Lee KM, Zhang J, Miller JH 4th, Schlage WK, Guedj E, Schneider T, Phillips B, Leroy P, Choukrallah MA, Sierro N, Buettner A, Xiang Y, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Wong ET, et al. Among authors: szostak j. Arch Toxicol. 2021 May;95(5):1805-1829. doi: 10.1007/s00204-021-03020-4. Epub 2021 May 7. Arch Toxicol. 2021. PMID: 33963423 Free PMC article.
A six-month systems toxicology inhalation/cessation study in ApoE-/- mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.
Phillips B, Szostak J, Titz B, Schlage WK, Guedj E, Leroy P, Vuillaume G, Martin F, Buettner A, Elamin A, Sewer A, Sierro N, Choukrallah MA, Schneider T, Ivanov NV, Teng C, Tung CK, Lim WT, Yeo YS, Vanscheeuwijck P, Peitsch MC, Hoeng J. Phillips B, et al. Among authors: szostak j. Food Chem Toxicol. 2019 Apr;126:113-141. doi: 10.1016/j.fct.2019.02.008. Epub 2019 Feb 12. Food Chem Toxicol. 2019. PMID: 30763686 Free article.
Structural, functional, and molecular impact on the cardiovascular system in ApoE-/- mice exposed to aerosol from candidate modified risk tobacco products, Carbon Heated Tobacco Product 1.2 and Tobacco Heating System 2.2, compared with cigarette smoke.
Szostak J, Titz B, Schlage WK, Guedj E, Sewer A, Phillips B, Leroy P, Buettner A, Neau L, Trivedi K, Martin F, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J. Szostak J, et al. Chem Biol Interact. 2020 Jan 5;315:108887. doi: 10.1016/j.cbi.2019.108887. Epub 2019 Nov 6. Chem Biol Interact. 2020. PMID: 31705857
355 results