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A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription.
Jiao X, Di Sante G, Casimiro MC, Tantos A, Ashton AW, Li Z, Quach Y, Bhargava D, Di Rocco A, Pupo C, Crosariol M, Lazar T, Tompa P, Wang C, Yu Z, Zhang Z, Aldaaysi K, Vadlamudi R, Mann M, Skordalakes E, Kossenkov A, Du Y, Pestell RG. Jiao X, et al. Among authors: di rocco a. Oncogenesis. 2024 Jan 8;13(1):4. doi: 10.1038/s41389-023-00502-1. Oncogenesis. 2024. PMID: 38191593 Free PMC article.
The membrane-associated form of cyclin D1 enhances cellular invasion.
Chen K, Jiao X, Ashton A, Di Rocco A, Pestell TG, Sun Y, Zhao J, Casimiro MC, Li Z, Lisanti MP, McCue PA, Shen D, Achilefu S, Rui H, Pestell RG. Chen K, et al. Among authors: di rocco a. Oncogenesis. 2020 Sep 18;9(9):83. doi: 10.1038/s41389-020-00266-y. Oncogenesis. 2020. PMID: 32948740 Free PMC article.
Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis.
Casimiro MC, Di Sante G, Di Rocco A, Loro E, Pupo C, Pestell TG, Bisetto S, Velasco-Velázquez MA, Jiao X, Li Z, Kusminski CM, Seifert EL, Wang C, Ly D, Zheng B, Shen CH, Scherer PE, Pestell RG. Casimiro MC, et al. Among authors: di rocco a, di sante g. Cancer Res. 2017 Jul 1;77(13):3391-3405. doi: 10.1158/0008-5472.CAN-16-0425. Epub 2017 May 18. Cancer Res. 2017. PMID: 28522753 Free PMC article.
Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth.
Pestell TG, Jiao X, Kumar M, Peck AR, Prisco M, Deng S, Li Z, Ertel A, Casimiro MC, Ju X, Di Rocco A, Di Sante G, Katiyar S, Shupp A, Lisanti MP, Jain P, Wu K, Rui H, Hooper DC, Yu Z, Goldman AR, Speicher DW, Laury-Kleintop L, Pestell RG. Pestell TG, et al. Among authors: di rocco a, di sante g. Oncotarget. 2017 Aug 4;8(47):81754-81775. doi: 10.18632/oncotarget.19953. eCollection 2017 Oct 10. Oncotarget. 2017. PMID: 29137220 Free PMC article.
v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1.
Ju X, Jiao X, Ertel A, Casimiro MC, Di Sante G, Deng S, Li Z, Di Rocco A, Zhan T, Hawkins A, Stoyanova T, Andò S, Fatatis A, Lisanti MP, Gomella LG, Languino LR, Pestell RG. Ju X, et al. Among authors: di rocco a, di sante g. Cancer Res. 2016 Nov 15;76(22):6723-6734. doi: 10.1158/0008-5472.CAN-15-3327. Epub 2016 Sep 15. Cancer Res. 2016. PMID: 27634768 Free PMC article.
The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses.
Li Z, Jiao X, Robertson AG, Di Sante G, Ashton AW, DiRocco A, Wang M, Zhao J, Addya S, Wang C, McCue PA, South AP, Cordon-Cardo C, Liu R, Patel K, Hamid R, Parmar J, DuHadaway JB, Jones SJM, Casimiro MC, Schultz N, Kossenkov A, Phoon LY, Chen H, Lan L, Sun Y, Iczkowski KA, Rui H, Pestell RG. Li Z, et al. Oncogene. 2023 Jun;42(22):1857-1873. doi: 10.1038/s41388-023-02668-9. Epub 2023 Apr 24. Oncogene. 2023. PMID: 37095257 Free PMC article.
The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses.
Li Z, Jiao X, Robertson AG, Sante GD, Ashton AW, DiRocco A, Wang M, Zhao J, Addya S, Wang C, McCue PA, South AP, Cordon-Cardo C, Liu R, Patel K, Hamid R, Parmar J, DuHadaway JB, Jones SJ, Casimiro MC, Schultz N, Kossenkov A, Phoon LY, Chen H, Lan L, Sun Y, Iczkowski KA, Rui H, Pestell RG. Li Z, et al. Res Sq [Preprint]. 2023 Jan 10:rs.3.rs-2423179. doi: 10.21203/rs.3.rs-2423179/v1. Res Sq. 2023. PMID: 36712010 Free PMC article. Updated. Preprint.
Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation.
Chen K, Jiao X, Di Rocco A, Shen D, Xu S, Ertel A, Yu Z, Di Sante G, Wang M, Li Z, Pestell TG, Casimiro MC, Skordalakes E, Achilefu S, Pestell RG. Chen K, et al. Among authors: di rocco a, di sante g. Cell Rep. 2023 Jun 27;42(6):112595. doi: 10.1016/j.celrep.2023.112595. Epub 2023 May 23. Cell Rep. 2023. PMID: 37224013 Free article. No abstract available.
225 results