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A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription.
Jiao X, Di Sante G, Casimiro MC, Tantos A, Ashton AW, Li Z, Quach Y, Bhargava D, Di Rocco A, Pupo C, Crosariol M, Lazar T, Tompa P, Wang C, Yu Z, Zhang Z, Aldaaysi K, Vadlamudi R, Mann M, Skordalakes E, Kossenkov A, Du Y, Pestell RG. Jiao X, et al. Among authors: skordalakes e. Oncogenesis. 2024 Jan 8;13(1):4. doi: 10.1038/s41389-023-00502-1. Oncogenesis. 2024. PMID: 38191593 Free PMC article.
Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation.
Chen K, Jiao X, Di Rocco A, Shen D, Xu S, Ertel A, Yu Z, Di Sante G, Wang M, Li Z, Pestell TG, Casimiro MC, Skordalakes E, Achilefu S, Pestell RG. Chen K, et al. Among authors: skordalakes e. Cell Rep. 2023 Jun 27;42(6):112595. doi: 10.1016/j.celrep.2023.112595. Epub 2023 May 23. Cell Rep. 2023. PMID: 37224013 Free article. No abstract available.
Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression.
Yeon M, Bertolini I, Agarwal E, Ghosh JC, Tang HY, Speicher DW, Keeney F, Sossey-Alaoui K, Pluskota E, Bialkowska K, Plow EF, Languino LR, Skordalakes E, Caino MC, Altieri DC. Yeon M, et al. Among authors: skordalakes e. J Biol Chem. 2023 Jun;299(6):104774. doi: 10.1016/j.jbc.2023.104774. Epub 2023 May 2. J Biol Chem. 2023. PMID: 37142218 Free PMC article.
Telomere dysfunction implicates POT1 in patients with idiopathic pulmonary fibrosis.
Kelich J, Aramburu T, van der Vis JJ, Showe L, Kossenkov A, van der Smagt J, Massink M, Schoemaker A, Hennekam E, Veltkamp M, van Moorsel CHM, Skordalakes E. Kelich J, et al. Among authors: skordalakes e. J Exp Med. 2022 May 2;219(5):e20211681. doi: 10.1084/jem.20211681. Epub 2022 Apr 14. J Exp Med. 2022. PMID: 35420632 Free PMC article.
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.
Miller KD, Pniewski K, Perry CE, Papp SB, Shaffer JD, Velasco-Silva JN, Casciano JC, Aramburu TM, Srikanth YVV, Cassel J, Skordalakes E, Kossenkov AV, Salvino JM, Schug ZT. Miller KD, et al. Among authors: skordalakes e. Cancer Res. 2021 Mar 1;81(5):1252-1264. doi: 10.1158/0008-5472.CAN-20-1847. Epub 2021 Jan 7. Cancer Res. 2021. PMID: 33414169 Free PMC article.
54 results