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Page 1
Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase.
Ritzefeld M, Zhang L, Xiao Z, Andrei SA, Boyd O, Masumoto N, Rodgers UR, Artelsmair M, Sefer L, Hayes A, Gavriil ES, Raynaud FI, Burke R, Blagg J, Rzepa HS, Siebold C, Magee AI, Lanyon-Hogg T, Tate EW. Ritzefeld M, et al. Among authors: siebold c. J Med Chem. 2024 Jan 25;67(2):1061-1078. doi: 10.1021/acs.jmedchem.3c01363. Epub 2024 Jan 10. J Med Chem. 2024. PMID: 38198226 Free PMC article.
Diverse genetic causes of amenorrhea in an ethnically homogeneous cohort and an evolving approach to diagnosis.
Bakhshalizadeh S, Afkhami F, Bell KM, Robevska G, van den Bergen J, Cronin S, Jaillard S, Ayers KL, Kumar P, Siebold C, Xiao Z, Tate EW, Danaei S, Farzadi L, Shahbazi S, Sinclair AH, Tucker EJ. Bakhshalizadeh S, et al. Among authors: siebold c. Mol Cell Endocrinol. 2024 Jun 1;587:112212. doi: 10.1016/j.mce.2024.112212. Epub 2024 Mar 22. Mol Cell Endocrinol. 2024. PMID: 38521400 Free article.
Mapping structural and dynamic divergence across the MBOAT family.
Ansell TB, Healy M, Coupland CE, Sansom MSP, Siebold C. Ansell TB, et al. Among authors: siebold c. Structure. 2024 Apr 5:S0969-2126(24)00096-0. doi: 10.1016/j.str.2024.03.014. Online ahead of print. Structure. 2024. PMID: 38636523 Free article.
The Energetics and Ion Coupling of Cholesterol Transport Through Patched1.
Ansell TB, Corey RA, Viti LV, Kinnebrew M, Rohatgi R, Siebold C, Sansom MSP. Ansell TB, et al. Among authors: siebold c. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528445. doi: 10.1101/2023.02.14.528445. bioRxiv. 2023. PMID: 36824746 Free PMC article. Updated. Preprint.
Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain.
Kinnebrew M, Woolley RE, Ansell TB, Byrne EFX, Frigui S, Luchetti G, Sircar R, Nachtergaele S, Mydock-McGrane L, Krishnan K, Newstead S, Sansom MSP, Covey DF, Siebold C, Rohatgi R. Kinnebrew M, et al. Among authors: siebold c. Sci Adv. 2022 Jun 3;8(22):eabm5563. doi: 10.1126/sciadv.abm5563. Epub 2022 Jun 3. Sci Adv. 2022. PMID: 35658032 Free PMC article.
118 results