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MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Cho MG, Kumar RJ, Lin CC, Boyer JA, Shahir JA, Fagan-Solis K, Simpson DA, Fan C, Foster CE, Goddard AM, Lerner LM, Ellington SW, Wang Q, Wang Y, Ho AY, Liu P, Perou CM, Zhang Q, McGinty RK, Purvis JE, Gupta GP. Cho MG, et al. Among authors: gupta gp. Nature. 2024 Jan;625(7995):585-592. doi: 10.1038/s41586-023-06889-6. Epub 2024 Jan 10. Nature. 2024. PMID: 38200309 Free PMC article.
Genetic determinants of cellular addiction to DNA polymerase theta.
Feng W, Simpson DA, Carvajal-Garcia J, Price BA, Kumar RJ, Mose LE, Wood RD, Rashid N, Purvis JE, Parker JS, Ramsden DA, Gupta GP. Feng W, et al. Among authors: gupta gp. Nat Commun. 2019 Sep 19;10(1):4286. doi: 10.1038/s41467-019-12234-1. Nat Commun. 2019. PMID: 31537809 Free PMC article.
Mechanisms of Immune Sensing of DNA Damage.
Goddard AM, Cho MG, Lerner LM, Gupta GP. Goddard AM, et al. Among authors: gupta gp. J Mol Biol. 2024 Feb 15;436(4):168424. doi: 10.1016/j.jmb.2023.168424. Epub 2023 Dec 29. J Mol Biol. 2024. PMID: 38159716 Review.
Evidence that the human cell cycle is a series of uncoupled, memoryless phases.
Chao HX, Fakhreddin RI, Shimerov HK, Kedziora KM, Kumar RJ, Perez J, Limas JC, Grant GD, Cook JG, Gupta GP, Purvis JE. Chao HX, et al. Among authors: gupta gp. Mol Syst Biol. 2019 Mar 18;15(3):e8604. doi: 10.15252/msb.20188604. Mol Syst Biol. 2019. PMID: 30886052 Free PMC article.
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities.
Krais JJ, Glass DJ, Chudoba I, Wang Y, Feng W, Simpson D, Patel P, Liu Z, Neumann-Domer R, Betsch RG, Bernhardy AJ, Bradbury AM, Conger J, Yueh WT, Nacson J, Pomerantz RT, Gupta GP, Testa JR, Johnson N. Krais JJ, et al. Among authors: gupta gp. Nat Commun. 2023 Nov 24;14(1):7714. doi: 10.1038/s41467-023-43446-1. Nat Commun. 2023. PMID: 38001070 Free PMC article.
159 results