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MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Cho MG, Kumar RJ, Lin CC, Boyer JA, Shahir JA, Fagan-Solis K, Simpson DA, Fan C, Foster CE, Goddard AM, Lerner LM, Ellington SW, Wang Q, Wang Y, Ho AY, Liu P, Perou CM, Zhang Q, McGinty RK, Purvis JE, Gupta GP. Cho MG, et al. Among authors: mcginty rk. Nature. 2024 Jan;625(7995):585-592. doi: 10.1038/s41586-023-06889-6. Epub 2024 Jan 10. Nature. 2024. PMID: 38200309 Free PMC article.
Structural basis of nucleosome-dependent cGAS inhibition.
Boyer JA, Spangler CJ, Strauss JD, Cesmat AP, Liu P, McGinty RK, Zhang Q. Boyer JA, et al. Among authors: mcginty rk. Science. 2020 Oct 23;370(6515):450-454. doi: 10.1126/science.abd0609. Epub 2020 Sep 10. Science. 2020. PMID: 32913000 Free PMC article.
Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Spangler CJ, Skrajna A, Foley CA, Nguyen A, Budziszewski GR, Azzam DN, Arteaga EC, Simmons HC, Smith CB, Wesley NA, Wilkerson EM, McPherson JE, Kireev D, James LI, Frye SV, Goldfarb D, McGinty RK. Spangler CJ, et al. Among authors: mcginty rk. Nat Chem Biol. 2023 May;19(5):624-632. doi: 10.1038/s41589-023-01256-y. Epub 2023 Feb 16. Nat Chem Biol. 2023. PMID: 36797403 Free PMC article.
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.
Scheuermann JC, de Ayala Alonso AG, Oktaba K, Ly-Hartig N, McGinty RK, Fraterman S, Wilm M, Muir TW, Müller J. Scheuermann JC, et al. Among authors: mcginty rk. Nature. 2010 May 13;465(7295):243-7. doi: 10.1038/nature08966. Epub 2010 May 2. Nature. 2010. PMID: 20436459 Free PMC article.
33 results