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The emerging role of hypoxia and environmental factors in inflammatory bowel disease.
Toxicol Sci. 2024 Mar 26;198(2):169-184. doi: 10.1093/toxsci/kfae004.
Toxicol Sci. 2024.
PMID: 38200624
Review.
Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis.
Kim H, Villareal LB, Liu Z, Haneef M, Falcon DM, Martin DR, Lee HJ, Dame MK, Attili D, Chen Y, Varani J, Spence JR, Kovbasnjuk O, Colacino JA, Lyssiotis CA, Lin HC, Shah YM, Xue X.
Kim H, et al. Among authors: villareal lb.
Adv Sci (Weinh). 2023 Apr;10(10):e2207693. doi: 10.1002/advs.202207693. Epub 2023 Jan 26.
Adv Sci (Weinh). 2023.
PMID: 36703617
Free PMC article.
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Iron promotes glycolysis to drive colon tumorigenesis.
Liu Z, Villareal L, Goodla L, Kim H, Falcon DM, Haneef M, Martin DR, Zhang L, Lee HJ, Kremer D, Lyssiotis CA, Shah YM, Lin HC, Lin HK, Xue X.
Liu Z, et al.
Biochim Biophys Acta Mol Basis Dis. 2023 Dec;1869(8):166846. doi: 10.1016/j.bbadis.2023.166846. Epub 2023 Aug 12.
Biochim Biophys Acta Mol Basis Dis. 2023.
PMID: 37579983
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Hypoxia-inducible factor 3α1 increases epithelial-to-mesenchymal transition and iron uptake to drive colorectal cancer liver metastasis.
Villareal LB, Falcon DM, Xie L, Xue X.
Villareal LB, et al.
Br J Cancer. 2024 May 1. doi: 10.1038/s41416-024-02699-3. Online ahead of print.
Br J Cancer. 2024.
PMID: 38693428
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