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The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over time.
Shahid A, MacLennan S, Jones BR, Sudderuddin H, Dang Z, Cobarrubias K, Duncan MC, Kinloch NN, Dapp MJ, Archin NM, Fischl MA, Ofotokun I, Adimora A, Gange S, Aouizerat B, Kuniholm MH, Kassaye S, Mullins JI, Goldstein H, Joy JB, Anastos K, Brumme ZL; MACS/WIHS combined cohort study (MWCSS). Shahid A, et al. Among authors: jones br. J Virol. 2024 Feb 20;98(2):e0165523. doi: 10.1128/jvi.01655-23. Epub 2024 Jan 12. J Virol. 2024. PMID: 38214547 Free PMC article.
Genetic Diversity, Compartmentalization, and Age of HIV Proviruses Persisting in CD4+ T Cell Subsets during Long-Term Combination Antiretroviral Therapy.
Jones BR, Miller RL, Kinloch NN, Tsai O, Rigsby H, Sudderuddin H, Shahid A, Ganase B, Brumme CJ, Harris M, Poon AFY, Brockman MA, Fromentin R, Chomont N, Joy JB, Brumme ZL. Jones BR, et al. J Virol. 2020 Feb 14;94(5):e01786-19. doi: 10.1128/JVI.01786-19. Print 2020 Feb 14. J Virol. 2020. PMID: 31776273 Free PMC article.
The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over time.
Shahid A, MacLennan S, Jones BR, Sudderuddin H, Dang Z, Cobamibias K, Duncan MC, Kinloch NN, Dapp MJ, Archin NM, Fischl MA, Ofotokun I, Adimora A, Gange S, Aouizerat B, Kuniholm MH, Kassaye S, Mullins JI, Goldstein H, Joy JB, Anastos K, Brumme ZL. Shahid A, et al. Among authors: jones br. Res Sq [Preprint]. 2023 Aug 16:rs.3.rs-3259040. doi: 10.21203/rs.3.rs-3259040/v1. Res Sq. 2023. PMID: 37645749 Free PMC article. Updated. Preprint.
HIV Diversity and Genetic Compartmentalization in Blood and Testes during Suppressive Antiretroviral Therapy.
Miller RL, Ponte R, Jones BR, Kinloch NN, Omondi FH, Jenabian MA, Dupuy FP, Fromentin R, Brassard P, Mehraj V, Chomont N, Poon AFY, Joy JB, Brumme ZL, Routy JP; ORCHID Study Group. Miller RL, et al. Among authors: jones br. J Virol. 2019 Aug 13;93(17):e00755-19. doi: 10.1128/JVI.00755-19. Print 2019 Sep 1. J Virol. 2019. PMID: 31189714 Free PMC article.
HIV Proviral Burden, Genetic Diversity, and Dynamics in Viremic Controllers Who Subsequently Initiated Suppressive Antiretroviral Therapy.
Omondi FH, Sudderuddin H, Shahid A, Kinloch NN, Jones BR, Miller RL, Tsai O, MacMillan D, Trocha A, Brockman MA, Brumme CJ, Joy JB, Liang R, Walker BD, Brumme ZL. Omondi FH, et al. Among authors: jones br. mBio. 2021 Dec 21;12(6):e0249021. doi: 10.1128/mBio.02490-21. Epub 2021 Nov 16. mBio. 2021. PMID: 34781741 Free PMC article.
460 results