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The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over time.
Shahid A, MacLennan S, Jones BR, Sudderuddin H, Dang Z, Cobarrubias K, Duncan MC, Kinloch NN, Dapp MJ, Archin NM, Fischl MA, Ofotokun I, Adimora A, Gange S, Aouizerat B, Kuniholm MH, Kassaye S, Mullins JI, Goldstein H, Joy JB, Anastos K, Brumme ZL; MACS/WIHS combined cohort study (MWCSS). Shahid A, et al. Among authors: mullins ji. J Virol. 2024 Feb 20;98(2):e0165523. doi: 10.1128/jvi.01655-23. Epub 2024 Jan 12. J Virol. 2024. PMID: 38214547 Free PMC article.
Lack of evidence for changing virulence of HIV-1 in North America.
Herbeck JT, Gottlieb GS, Li X, Hu Z, Detels R, Phair J, Rinaldo C, Jacobson LP, Margolick JB, Mullins JI. Herbeck JT, et al. Among authors: mullins ji. PLoS One. 2008 Feb 6;3(2):e1525. doi: 10.1371/journal.pone.0001525. PLoS One. 2008. PMID: 18253479 Free PMC article.
Multistage genomewide association study identifies a locus at 1q41 associated with rate of HIV-1 disease progression to clinical AIDS.
Herbeck JT, Gottlieb GS, Winkler CA, Nelson GW, An P, Maust BS, Wong KG, Troyer JL, Goedert JJ, Kessing BD, Detels R, Wolinsky SM, Martinson J, Buchbinder S, Kirk GD, Jacobson LP, Margolick JB, Kaslow RA, O'Brien SJ, Mullins JI. Herbeck JT, et al. Among authors: mullins ji. J Infect Dis. 2010 Feb 15;201(4):618-26. doi: 10.1086/649842. J Infect Dis. 2010. PMID: 20064070 Free PMC article.
396 results