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Inherited blood cancer predisposition through altered transcription elongation.
Zhao J, Cato LD, Arora UP, Bao EL, Bryant SC, Williams N, Jia Y, Goldman SR, Nangalia J, Erb MA, Vos SM, Armstrong SA, Sankaran VG. Zhao J, et al. Among authors: sankaran vg. Cell. 2024 Feb 1;187(3):642-658.e19. doi: 10.1016/j.cell.2023.12.016. Epub 2024 Jan 12. Cell. 2024. PMID: 38218188 Free article.
Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.
Giani FC, Fiorini C, Wakabayashi A, Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G, Steinberg-Shemer O, Guo MH, Esko T, Tong W, Brugnara C, Hirschhorn JN, Weiss MJ, Zon LI, Chou ST, French DL, Musunuru K, Sankaran VG. Giani FC, et al. Among authors: sankaran vg. Cell Stem Cell. 2016 Jan 7;18(1):73-78. doi: 10.1016/j.stem.2015.09.015. Epub 2015 Oct 22. Cell Stem Cell. 2016. PMID: 26607381 Free PMC article.
Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease.
Raffield LM, Ulirsch JC, Naik RP, Lessard S, Handsaker RE, Jain D, Kang HM, Pankratz N, Auer PL, Bao EL, Smith JD, Lange LA, Lange EM, Li Y, Thornton TA, Young BA, Abecasis GR, Laurie CC, Nickerson DA, McCarroll SA, Correa A, Wilson JG; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Hematology & Hemostasis, Diabetes, and Structural Variation TOPMed Working Groups; Lettre G, Sankaran VG, Reiner AP. Raffield LM, et al. Among authors: sankaran vg. PLoS Genet. 2018 Mar 28;14(3):e1007293. doi: 10.1371/journal.pgen.1007293. eCollection 2018 Mar. PLoS Genet. 2018. PMID: 29590102 Free PMC article.
Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.
Bao EL, Lareau CA, Brugnara C, Fulcher IR, Barau C, Moutereau S, Habibi A, Badaoui B, Berkenou J, Bartolucci P, Galactéros F, Platt OS, Mahaney M, Sankaran VG. Bao EL, et al. Among authors: sankaran vg. Am J Hematol. 2019 May;94(5):522-527. doi: 10.1002/ajh.25421. Epub 2019 Feb 6. Am J Hematol. 2019. PMID: 30680775 Free PMC article. Clinical Trial.
Interrogation of human hematopoiesis at single-cell and single-variant resolution.
Ulirsch JC, Lareau CA, Bao EL, Ludwig LS, Guo MH, Benner C, Satpathy AT, Kartha VK, Salem RM, Hirschhorn JN, Finucane HK, Aryee MJ, Buenrostro JD, Sankaran VG. Ulirsch JC, et al. Among authors: sankaran vg. Nat Genet. 2019 Apr;51(4):683-693. doi: 10.1038/s41588-019-0362-6. Epub 2019 Mar 11. Nat Genet. 2019. PMID: 30858613 Free PMC article.
Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis.
Ludwig LS, Lareau CA, Bao EL, Nandakumar SK, Muus C, Ulirsch JC, Chowdhary K, Buenrostro JD, Mohandas N, An X, Aryee MJ, Regev A, Sankaran VG. Ludwig LS, et al. Among authors: sankaran vg. Cell Rep. 2019 Jun 11;27(11):3228-3240.e7. doi: 10.1016/j.celrep.2019.05.046. Cell Rep. 2019. PMID: 31189107 Free PMC article.
Stabilizing HIF to Ameliorate Anemia.
Voit RA, Sankaran VG. Voit RA, et al. Among authors: sankaran vg. Cell. 2020 Jan 9;180(1):6. doi: 10.1016/j.cell.2019.12.010. Cell. 2020. PMID: 31951520 Free article.
207 results