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Overview of the Knowledge Management Center for Illuminating the Druggable Genome.
Oprea TI, Bologa C, Holmes J, Mathias S, Metzger VT, Waller A, Yang JJ, Leach AR, Jensen LJ, Kelleher KJ, Sheils TK, Mathé E, Avram S, Edwards JS. Oprea TI, et al. Among authors: avram s. Drug Discov Today. 2024 Mar;29(3):103882. doi: 10.1016/j.drudis.2024.103882. Epub 2024 Jan 11. Drug Discov Today. 2024. PMID: 38218214 Free article. Review.
DrugCentral 2021 supports drug discovery and repositioning.
Avram S, Bologa CG, Holmes J, Bocci G, Wilson TB, Nguyen DT, Curpan R, Halip L, Bora A, Yang JJ, Knockel J, Sirimulla S, Ursu O, Oprea TI. Avram S, et al. Nucleic Acids Res. 2021 Jan 8;49(D1):D1160-D1169. doi: 10.1093/nar/gkaa997. Nucleic Acids Res. 2021. PMID: 33151287 Free PMC article.
Exploring DrugCentral: from molecular structures to clinical effects.
Halip L, Avram S, Curpan R, Borota A, Bora A, Bologa C, Oprea TI. Halip L, et al. Among authors: avram s. J Comput Aided Mol Des. 2023 Dec;37(12):681-694. doi: 10.1007/s10822-023-00529-x. Epub 2023 Sep 14. J Comput Aided Mol Des. 2023. PMID: 37707619 Free PMC article. Review.
Off-Patent Drug Repositioning.
Avram S, Curpan R, Halip L, Bora A, Oprea TI. Avram S, et al. J Chem Inf Model. 2020 Dec 28;60(12):5746-5753. doi: 10.1021/acs.jcim.0c00826. Epub 2020 Sep 15. J Chem Inf Model. 2020. PMID: 32877182
Novel drug targets in 2020.
Avram S, Halip L, Curpan R, Oprea TI. Avram S, et al. Nat Rev Drug Discov. 2021 May;20(5):333. doi: 10.1038/d41573-021-00057-z. Nat Rev Drug Discov. 2021. PMID: 33824485 No abstract available.
Novel drug targets in 2021.
Avram S, Halip L, Curpan R, Oprea TI. Avram S, et al. Nat Rev Drug Discov. 2022 May;21(5):328. doi: 10.1038/d41573-022-00057-7. Nat Rev Drug Discov. 2022. PMID: 35361900 No abstract available.
Novel drug targets in 2019.
Avram S, Halip L, Curpan R, Oprea TI. Avram S, et al. Nat Rev Drug Discov. 2020 May;19(5):300. doi: 10.1038/d41573-020-00052-w. Nat Rev Drug Discov. 2020. PMID: 32273590 No abstract available.
134 results