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Dihydropyrimidine dehydrogenase gene variants for predicting grade 4-5 fluoropyrimidine-induced toxicity: FUSAFE individual patient data meta-analysis.
Le Teuff G, Cozic N, Boyer JC, Boige V, Diasio RB, Taieb J, Meulendijks D, Palles C, Schwab M, Deenen M, Largiadèr CR, Marinaki A, Jennings BA, Wettergren Y, Di Paolo A, Gross E, Budai B, Ackland SP, van Kuilenburg ABP, McLeod HL, Milano G, Thomas F, Loriot MA, Kerr D, Schellens JHM, Laurent-Puig P, Shi Q, Pignon JP, Etienne-Grimaldi MC; FUSAFE collaborative group. Le Teuff G, et al. Among authors: diasio rb. Br J Cancer. 2024 Mar;130(5):808-818. doi: 10.1038/s41416-023-02517-2. Epub 2024 Jan 15. Br J Cancer. 2024. PMID: 38225422
Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD).
Zhang T, Ambrodji A, Huang H, Bouchonville KJ, Etheridge AS, Schmidt RE, Bembenek BM, Temesgen ZB, Wang Z, Innocenti F, Stroka D, Diasio RB, Largiadèr CR, Offer SM. Zhang T, et al. Among authors: diasio rb. bioRxiv [Preprint]. 2024 Mar 16:2023.11.01.565230. doi: 10.1101/2023.11.01.565230. bioRxiv. 2024. PMID: 37961517 Free PMC article. Updated. Preprint.
DPYD Testing: Time to Put Patient Safety First.
Baker SD, Bates SE, Brooks GA, Dahut WL, Diasio RB, El-Deiry WS, Evans WE, Figg WD, Hertz DL, Hicks JK, Kamath S, Kasi PM, Knepper TC, McLeod HL, O'Donnell PH, Relling MV, Rudek MA, Sissung TM, Smith DM, Sparreboom A, Swain SM, Walko CM. Baker SD, et al. Among authors: diasio rb. J Clin Oncol. 2023 May 20;41(15):2701-2705. doi: 10.1200/JCO.22.02364. Epub 2023 Feb 23. J Clin Oncol. 2023. PMID: 36821823 Free PMC article. No abstract available.
Cancer Mortality Rates Increasing vs Cardiovascular Disease Mortality Decreasing in the World: Future Implications.
ReFaey K, Tripathi S, Grewal SS, Bhargav AG, Quinones DJ, Chaichana KL, Antwi SO, Cooper LT, Meyer FB, Dronca RS, Diasio RB, Quinones-Hinojosa A. ReFaey K, et al. Among authors: diasio rb. Mayo Clin Proc Innov Qual Outcomes. 2021 Jun 8;5(3):645-653. doi: 10.1016/j.mayocpiqo.2021.05.005. eCollection 2021 Jun. Mayo Clin Proc Innov Qual Outcomes. 2021. PMID: 34195556 Free PMC article.
Pharmacogenomic-Guided Therapy in Colorectal Cancer.
Diasio RB, Innocenti F, Offer SM. Diasio RB, et al. Clin Pharmacol Ther. 2021 Sep;110(3):616-625. doi: 10.1002/cpt.2334. Epub 2021 Jul 10. Clin Pharmacol Ther. 2021. PMID: 34114648 Review.
Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5-fluorouracil toxicity.
Hamzic S, Schärer D, Offer SM, Meulendijks D, Nakas C, Diasio RB, Fontana S, Wehrli M, Schürch S, Amstutz U, Largiadèr CR. Hamzic S, et al. Among authors: diasio rb. Br J Clin Pharmacol. 2021 Aug;87(8):3234-3243. doi: 10.1111/bcp.14742. Epub 2021 Mar 30. Br J Clin Pharmacol. 2021. PMID: 33491253 Free PMC article.
220 results