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In situ modeling of acquired resistance to RTK/RAS-pathway-targeted therapies.
iScience. 2023 Dec 11;27(1):108711. doi: 10.1016/j.isci.2023.108711. eCollection 2024 Jan 19.
iScience. 2023.
PMID: 38226159
Free PMC article.
In situ modeling of acquired resistance to RTK/RAS pathway targeted therapies.
Sealover NE, Theard PL, Hughes JM, Linke AJ, Daley BR, Kortum RL.
Sealover NE, et al. Among authors: daley br.
bioRxiv [Preprint]. 2023 Jun 28:2023.01.27.525958. doi: 10.1101/2023.01.27.525958.
bioRxiv. 2023.
PMID: 36747633
Free PMC article.
Updated.
Preprint.
Item in Clipboard
SOS2 regulates the threshold of mutant EGFR-dependent oncogenesis.
Theard PL, Linke AJ, Sealover NE, Daley BR, Yang J, Cox K, Kortum RL.
Theard PL, et al. Among authors: daley br.
bioRxiv [Preprint]. 2023 Jun 29:2023.01.20.524989. doi: 10.1101/2023.01.20.524989.
bioRxiv. 2023.
PMID: 37425733
Free PMC article.
Updated.
Preprint.
Item in Clipboard
SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma.
Daley BR, Sealover NE, Sheffels E, Hughes JM, Gerlach D, Hofmann MH, Kostyrko K, Mair B, Linke A, Beckley Z, Frank A, Dalgard C, Kortum RL.
Daley BR, et al.
bioRxiv [Preprint]. 2023 Dec 15:2023.12.07.570642. doi: 10.1101/2023.12.07.570642.
bioRxiv. 2023.
PMID: 38106234
Free PMC article.
Preprint.
Item in Clipboard
SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma.
Theard PL, Linke AJ, Sealover NE, Daley BR, Yang J, Cox K, Kortum RL.
Theard PL, et al. Among authors: daley br.
Mol Oncol. 2024 Mar;18(3):641-661. doi: 10.1002/1878-0261.13564. Epub 2024 Jan 18.
Mol Oncol. 2024.
PMID: 38073064
Free PMC article.
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SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status.
Daley BR, Vieira HM, Rao C, Hughes JM, Beckley ZM, Huisman DH, Chatterjee D, Sealover NE, Cox K, Askew JW, Svoboda RA, Fisher KW, Lewis RE, Kortum RL.
Daley BR, et al.
Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2313137120. doi: 10.1073/pnas.2313137120. Epub 2023 Nov 16.
Proc Natl Acad Sci U S A. 2023.
PMID: 37972068
Free PMC article.
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