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Page 1
Five dominant dimensions of brain aging are identified via deep learning: associations with clinical, lifestyle, and genetic measures.
Yang Z, Wen J, Erus G, Govindarajan ST, Melhem R, Mamourian E, Cui Y, Srinivasan D, Abdulkadir A, Parmpi P, Wittfeld K, Grabe HJ, Bülow R, Frenzel S, Tosun D, Bilgel M, An Y, Yi D, Marcus DS, LaMontagne P, Benzinger TLS, Heckbert SR, Austin TR, Waldstein SR, Evans MK, Zonderman AB, Launer LJ, Sotiras A, Espeland MA, Masters CL, Maruff P, Fripp J, Toga A, O'Bryant S, Chakravarty MM, Villeneuve S, Johnson SC, Morris JC, Albert MS, Yaffe K, Völzke H, Ferrucci L, Bryan NR, Shinohara RT, Fan Y, Habes M, Lalousis PA, Koutsouleris N, Wolk DA, Resnick SM, Shou H, Nasrallah IM, Davatzikos C. Yang Z, et al. Among authors: erus g. medRxiv [Preprint]. 2023 Dec 30:2023.12.29.23300642. doi: 10.1101/2023.12.29.23300642. medRxiv. 2023. PMID: 38234857 Free PMC article. Preprint.
Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability.
Wen J, Skampardoni I, Tian YE, Yang Z, Cui Y, Erus G, Hwang G, Varol E, Boquet-Pujadas A, Chand GB, Nasrallah I, Satterthwaite T, Shou H, Shen L, Toga AW, Zaleskey A, Davatzikos C. Wen J, et al. Among authors: erus g. medRxiv [Preprint]. 2023 Aug 24:2023.08.16.23294179. doi: 10.1101/2023.08.16.23294179. medRxiv. 2023. PMID: 37662256 Free PMC article. Preprint.
The Genetic Architecture of Multimodal Human Brain Age.
Wen J, Zhao B, Yang Z, Erus G, Skampardoni I, Mamourian E, Cui Y, Hwang G, Bao J, Boquet-Pujadas A, Zhou Z, Veturi Y, Ritchie MD, Shou H, Thompson PM, Shen L, Toga AW, Davatzikos C. Wen J, et al. Among authors: erus g. bioRxiv [Preprint]. 2023 Sep 30:2023.04.13.536818. doi: 10.1101/2023.04.13.536818. bioRxiv. 2023. PMID: 37333190 Free PMC article. Updated. Preprint.
A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure.
Yang Z, Nasrallah IM, Shou H, Wen J, Doshi J, Habes M, Erus G, Abdulkadir A, Resnick SM, Albert MS, Maruff P, Fripp J, Morris JC, Wolk DA, Davatzikos C; iSTAGING Consortium; Baltimore Longitudinal Study of Aging (BLSA); Alzheimer’s Disease Neuroimaging Initiative (ADNI). Yang Z, et al. Among authors: erus g. Nat Commun. 2021 Dec 3;12(1):7065. doi: 10.1038/s41467-021-26703-z. Nat Commun. 2021. PMID: 34862382 Free PMC article.
Gene-SGAN: a method for discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering.
Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, Albert MS, Johnson SC, Morris JC, LaMontagne P, Marcus DS, Benzinger TLS, Wolk DA, Shen L, Bao J, Resnick SM, Shou H, Nasrallah IM, Davatzikos C. Yang Z, et al. Among authors: erus g. ArXiv [Preprint]. 2023 Jan 25:arXiv:2301.10772v1. ArXiv. 2023. PMID: 36748000 Free PMC article. Updated. Preprint.
Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering.
Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, Albert MS, Johnson SC, Morris JC, LaMontagne P, Marcus DS, Benzinger TLS, Wolk DA, Shen L, Bao J, Resnick SM, Shou H, Nasrallah IM, Davatzikos C. Yang Z, et al. Among authors: erus g. Nat Commun. 2024 Jan 8;15(1):354. doi: 10.1038/s41467-023-44271-2. Nat Commun. 2024. PMID: 38191573 Free PMC article.
MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide.
Bashyam VM, Erus G, Doshi J, Habes M, Nasrallah I, Truelove-Hill M, Srinivasan D, Mamourian L, Pomponio R, Fan Y, Launer LJ, Masters CL, Maruff P, Zhuo C, Völzke H, Johnson SC, Fripp J, Koutsouleris N, Satterthwaite TD, Wolf D, Gur RE, Gur RC, Morris J, Albert MS, Grabe HJ, Resnick S, Bryan RN, Wolk DA, Shou H, Davatzikos C. Bashyam VM, et al. Among authors: erus g. Brain. 2020 Jul 1;143(7):2312-2324. doi: 10.1093/brain/awaa160. Brain. 2020. PMID: 32591831 Free PMC article.
The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans.
Habes M, Pomponio R, Shou H, Doshi J, Mamourian E, Erus G, Nasrallah I, Launer LJ, Rashid T, Bilgel M, Fan Y, Toledo JB, Yaffe K, Sotiras A, Srinivasan D, Espeland M, Masters C, Maruff P, Fripp J, Völzk H, Johnson SC, Morris JC, Albert MS, Miller MI, Bryan RN, Grabe HJ, Resnick SM, Wolk DA, Davatzikos C; iSTAGING consortium, the Preclinical AD consortium, the ADNI, and the CARDIA studies. Habes M, et al. Among authors: erus g. Alzheimers Dement. 2021 Jan;17(1):89-102. doi: 10.1002/alz.12178. Epub 2020 Sep 13. Alzheimers Dement. 2021. PMID: 32920988 Free PMC article.
Deep Generative Medical Image Harmonization for Improving Cross-Site Generalization in Deep Learning Predictors.
Bashyam VM, Doshi J, Erus G, Srinivasan D, Abdulkadir A, Singh A, Habes M, Fan Y, Masters CL, Maruff P, Zhuo C, Völzke H, Johnson SC, Fripp J, Koutsouleris N, Satterthwaite TD, Wolf DH, Gur RE, Gur RC, Morris JC, Albert MS, Grabe HJ, Resnick SM, Bryan NR, Wittfeld K, Bülow R, Wolk DA, Shou H, Nasrallah IM, Davatzikos C; iSTAGING and PHENOM consortia. Bashyam VM, et al. Among authors: erus g. J Magn Reson Imaging. 2022 Mar;55(3):908-916. doi: 10.1002/jmri.27908. Epub 2021 Sep 25. J Magn Reson Imaging. 2022. PMID: 34564904 Free PMC article.
Disentangling Alzheimer's disease neurodegeneration from typical brain ageing using machine learning.
Hwang G, Abdulkadir A, Erus G, Habes M, Pomponio R, Shou H, Doshi J, Mamourian E, Rashid T, Bilgel M, Fan Y, Sotiras A, Srinivasan D, Morris JC, Albert MS, Bryan NR, Resnick SM, Nasrallah IM, Davatzikos C, Wolk DA; from the iSTAGING consortium; ADNI. Hwang G, et al. Among authors: erus g. Brain Commun. 2022 May 7;4(3):fcac117. doi: 10.1093/braincomms/fcac117. eCollection 2022. Brain Commun. 2022. PMID: 35611306 Free PMC article.
138 results