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Five dominant dimensions of brain aging are identified via deep learning: associations with clinical, lifestyle, and genetic measures.
Yang Z, Wen J, Erus G, Govindarajan ST, Melhem R, Mamourian E, Cui Y, Srinivasan D, Abdulkadir A, Parmpi P, Wittfeld K, Grabe HJ, Bülow R, Frenzel S, Tosun D, Bilgel M, An Y, Yi D, Marcus DS, LaMontagne P, Benzinger TLS, Heckbert SR, Austin TR, Waldstein SR, Evans MK, Zonderman AB, Launer LJ, Sotiras A, Espeland MA, Masters CL, Maruff P, Fripp J, Toga A, O'Bryant S, Chakravarty MM, Villeneuve S, Johnson SC, Morris JC, Albert MS, Yaffe K, Völzke H, Ferrucci L, Bryan NR, Shinohara RT, Fan Y, Habes M, Lalousis PA, Koutsouleris N, Wolk DA, Resnick SM, Shou H, Nasrallah IM, Davatzikos C. Yang Z, et al. Among authors: villeneuve s. medRxiv [Preprint]. 2023 Dec 30:2023.12.29.23300642. doi: 10.1101/2023.12.29.23300642. medRxiv. 2023. PMID: 38234857 Free PMC article. Preprint.
Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment.
Strikwerda-Brown C, Hobbs DA, Gonneaud J, St-Onge F, Binette AP, Ozlen H, Provost K, Soucy JP, Buckley RF, Benzinger TLS, Morris JC, Villemagne VL, Doré V, Sperling RA, Johnson KA, Rowe CC, Gordon BA, Poirier J, Breitner JCS, Villeneuve S; PREVENT-AD, HABS, and AIBL Research Groups. Strikwerda-Brown C, et al. Among authors: villeneuve s. JAMA Neurol. 2022 Oct 1;79(10):975-985. doi: 10.1001/jamaneurol.2022.2379. JAMA Neurol. 2022. PMID: 35907254 Free PMC article.
A longitudinal resource for population neuroscience of school-age children and adolescents in China.
Fan XR, Wang YS, Chang D, Yang N, Rong MJ, Zhang Z, He Y, Hou X, Zhou Q, Gong ZQ, Cao LZ, Dong HM, Nie JJ, Chen LZ, Zhang Q, Zhang JX, Zhang L, Li HJ, Bao M, Chen A, Chen J, Chen X, Ding J, Dong X, Du Y, Feng C, Feng T, Fu X, Ge LK, Hong B, Hu X, Huang W, Jiang C, Li L, Li Q, Li S, Liu X, Mo F, Qiu J, Su XQ, Wei GX, Wu Y, Xia H, Yan CG, Yan ZX, Yang X, Zhang W, Zhao K, Zhu L; Chinese Color Nest Consortium (CCNC); Lifespan Brain Chart Consortium (LBCC); Zuo XN. Fan XR, et al. Sci Data. 2023 Aug 21;10(1):545. doi: 10.1038/s41597-023-02377-8. Sci Data. 2023. PMID: 37604823 Free PMC article.
Locus coeruleus integrity is related to an exploitation-based decision-making bias in older adulthood.
Turner GR, Hewan P, Wearn A, van Dooren R, Wyatt L, Leppert IR, Baracchini G, Hughes C, Williams KM, Sylvain E, Tremblay-Mercier J, Poirier J, Villeneuve S, Tardif C, Spreng RN; PREVENT-AD Research Group. Turner GR, et al. Among authors: villeneuve s. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2322617121. doi: 10.1073/pnas.2322617121. Epub 2024 May 21. Proc Natl Acad Sci U S A. 2024. PMID: 38771873 Free article.
Plasma p-tau217 predicts cognitive impairments up to ten years before onset in normal older adults.
Yakoub Y, Gonzalez-Ortiz F, Ashton NJ, Déry C, Strikwerda-Brown C, St-Onge F, Ourry V, Schöll M, Geddes MR, Ducharme S, Montembeault M, Rosa-Neto P, Soucy JP, Breitner JCS, Zetterberg H, Blennow K, Poirier J, Villeneuve S; PREVENT-AD Research Group. Yakoub Y, et al. Among authors: villeneuve s. medRxiv [Preprint]. 2024 May 9:2024.05.09.24307120. doi: 10.1101/2024.05.09.24307120. medRxiv. 2024. PMID: 38766113 Free PMC article. Preprint.
Atypical brain aging and its association with working memory performance in major depressive disorder.
Ho NCW, Bethlehem RA, Seidlitz J, Nogovitsyn N, Metzak P, Ballester PL, Hassel S, Rotzinger S, Poppenk J, Lam RW, Taylor VH, Milev R; Lifespan Brain Chart Consortium; Bullmore ET, Alexander-Bloch AF, Frey BN, Harkness KL, Addington J, Kennedy SH, Dunlop K. Ho NCW, et al. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Apr 26:S2451-9022(24)00110-1. doi: 10.1016/j.bpsc.2024.04.008. Online ahead of print. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024. PMID: 38679324
Contactin 5 and Apolipoproteins Interplay in Alzheimer's Disease.
Dauar MT, Picard C, Labonté A, Breitner J, Rosa-Neto P, Villeneuve S, Poirier J; PREVENT-AD Research Group. Dauar MT, et al. Among authors: villeneuve s. J Alzheimers Dis. 2024;98(4):1361-1375. doi: 10.3233/JAD-231003. J Alzheimers Dis. 2024. PMID: 38578887
Structural white matter properties and cognitive resilience to tau pathology.
Qiu T, Liu ZQ, Rheault F, Legarreta JH, Valcourt Caron A, St-Onge F, Strikwerda-Brown C, Metz A, Dadar M, Soucy JP, Pichet Binette A, Spreng RN, Descoteaux M, Villeneuve S; PREVENT‐AD Research Group. Qiu T, et al. Among authors: villeneuve s. Alzheimers Dement. 2024 May;20(5):3364-3377. doi: 10.1002/alz.13776. Epub 2024 Apr 1. Alzheimers Dement. 2024. PMID: 38561254 Free PMC article.
143 results