Rando TA - Search Results

1

Depletion of SAM leading to loss of heterochromatin drives muscle stem cell ageing.

Kang J, Benjamin DI, Kim S, Salvi JS, Dhaliwal G, Lam R, Goshayeshi A, Brett JO, Liu L, Rando TA. Kang J, et al. Among authors: rando ta. Nat Metab. 2024 Jan;6(1):153-168. doi: 10.1038/s42255-023-00955-z. Epub 2024 Jan 19. Nat Metab. 2024. PMID: 38243132

2

Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1.

Brett JO, Arjona M, Ikeda M, Quarta M, de Morrée A, Egner IM, Perandini LA, Ishak HD, Goshayeshi A, Benjamin DI, Both P, Rodríguez-Mateo C, Betley MJ, Wyss-Coray T, Rando TA. Brett JO, et al. Among authors: rando ta. Nat Metab. 2020 Apr;2(4):307-317. doi: 10.1038/s42255-020-0190-0. Epub 2020 Apr 13. Nat Metab. 2020. PMID: 32601609 Free PMC article.

3

Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging.

Benjamin DI, Brett JO, Both P, Benjamin JS, Ishak HL, Kang J, Kim S, Chung M, Arjona M, Nutter CW, Tan JH, Krishnan AK, Dulay H, Louie SM, de Morree A, Nomura DK, Rando TA. Benjamin DI, et al. Among authors: rando ta. Cell Metab. 2023 Mar 7;35(3):472-486.e6. doi: 10.1016/j.cmet.2023.02.001. Epub 2023 Feb 27. Cell Metab. 2023. PMID: 36854304 Free PMC article.

4

Manifestations and mechanisms of stem cell aging.

Liu L, Rando TA. Liu L, et al. Among authors: rando ta. J Cell Biol. 2011 Apr 18;193(2):257-66. doi: 10.1083/jcb.201010131. J Cell Biol. 2011. PMID: 21502357 Free PMC article. Review.

5

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).

Rodgers JT, King KY, Brett JO, Cromie MJ, Charville GW, Maguire KK, Brunson C, Mastey N, Liu L, Tsai CR, Goodell MA, Rando TA. Rodgers JT, et al. Among authors: rando ta. Nature. 2014 Jun 19;510(7505):393-6. doi: 10.1038/nature13255. Epub 2014 May 25. Nature. 2014. PMID: 24870234 Free PMC article.

6

An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy.

Quarta M, Brett JO, DiMarco R, De Morree A, Boutet SC, Chacon R, Gibbons MC, Garcia VA, Su J, Shrager JB, Heilshorn S, Rando TA. Quarta M, et al. Among authors: rando ta. Nat Biotechnol. 2016 Jul;34(7):752-9. doi: 10.1038/nbt.3576. Epub 2016 May 30. Nat Biotechnol. 2016. PMID: 27240197 Free PMC article.

7

Tubastatin A maintains adult skeletal muscle stem cells in a quiescent state ex vivo and improves their engraftment ability in vivo.

Arjona M, Goshayeshi A, Rodriguez-Mateo C, Brett JO, Both P, Ishak H, Rando TA. Arjona M, et al. Among authors: rando ta. Stem Cell Reports. 2022 Jan 11;17(1):82-95. doi: 10.1016/j.stemcr.2021.11.012. Stem Cell Reports. 2022. PMID: 35021050 Free PMC article.

8

ATR activity controls stem cell quiescence via the cyclin F-SCF complex.

Salvi JS, Kang J, Kim S, Colville AJ, de Morrée A, Billeskov TB, Larsen MC, Kanugovi A, van Velthoven CTJ, Cimprich KA, Rando TA. Salvi JS, et al. Among authors: rando ta. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2115638119. doi: 10.1073/pnas.2115638119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476521 Free PMC article.

9

Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling.

Benjamin DI, Both P, Benjamin JS, Nutter CW, Tan JH, Kang J, Machado LA, Klein JDD, de Morree A, Kim S, Liu L, Dulay H, Feraboli L, Louie SM, Nomura DK, Rando TA. Benjamin DI, et al. Among authors: rando ta. Cell Metab. 2022 Jun 7;34(6):902-918.e6. doi: 10.1016/j.cmet.2022.04.012. Epub 2022 May 17. Cell Metab. 2022. PMID: 35584694 Free PMC article.

10

Alive and well? Exploring disease by studying lifespan.

Brett JO, Rando TA. Brett JO, et al. Among authors: rando ta. Curr Opin Genet Dev. 2014 Jun;26:33-40. doi: 10.1016/j.gde.2014.05.004. Epub 2014 Jul 6. Curr Opin Genet Dev. 2014. PMID: 25005743 Free PMC article. Review.

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