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Analytical performance of the FDA-cleared Parsortix® PC1 system.
Templeman A, Miller MC, Cooke MJ, O'Shannessy DJ, Gurung Y, Pereira T, Peters SG, Piano M, Teo M, Khazan N, Kim K, Cohen E, Lopez HB, Alvarez F, Ciccioli M, Pailhes-Jimenez AS. Templeman A, et al. J Circ Biomark. 2023 Aug 7;12:26-33. doi: 10.33393/jcb.2023.2629. eCollection 2023 Jan-Dec. J Circ Biomark. 2023. PMID: 37601320 Free PMC article.
TBX2 acts as a potent transcriptional silencer of tumour suppressor genes through interaction with the CoREST complex to sustain the proliferation of breast cancers.
McIntyre AJ, Angel CZ, Smith JS, Templeman A, Beattie K, Beattie S, Ormrod A, Devlin E, McGreevy C, Bothwell C, Eddie SL, Buckley NE, Williams R, Mullan PB. McIntyre AJ, et al. Among authors: templeman a. Nucleic Acids Res. 2022 Jun 24;50(11):6154-6173. doi: 10.1093/nar/gkac494. Nucleic Acids Res. 2022. PMID: 35687133 Free PMC article.
Development of a potent and selective cell penetrant Legumain inhibitor.
Ness KA, Eddie SL, Higgins CA, Templeman A, D'Costa Z, Gaddale KK, Bouzzaoui S, Jordan L, Janssen D, Harrison T, Burkamp F, Young A, Burden R, Scott CJ, Mullan PB, Williams R. Ness KA, et al. Among authors: templeman a. Bioorg Med Chem Lett. 2015 Dec 1;25(23):5642-5. doi: 10.1016/j.bmcl.2015.10.001. Epub 2015 Oct 9. Bioorg Med Chem Lett. 2015. PMID: 26522952
P3 SAR exploration of biphenyl carbamate based Legumain inhibitors.
Higgins C, Bouazzaoui S, Gaddale K, D'Costa Z, Templeman A, O'Rourke M, Young A, Scott C, Harrison T, Mullan P, Williams R. Higgins C, et al. Among authors: templeman a. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2521-4. doi: 10.1016/j.bmcl.2014.04.002. Epub 2014 Apr 12. Bioorg Med Chem Lett. 2014. PMID: 24775305