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Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials.
Rivellese F, Nerviani A, Giorli G, Warren L, Jaworska E, Bombardieri M, Lewis MJ, Humby F, Pratt AG, Filer A, Gendi N, Cauli A, Choy E, McInnes I, Durez P, Edwards CJ, Buch MH, Gremese E, Taylor PC, Ng N, Cañete JD, Raizada S, McKay ND, Jadon D, Sainaghi PP, Stratton R, Ehrenstein MR, Ho P, Pereira JP, Dasgupta B, Gorman C, Galloway J, Chinoy H, van der Heijde D, Sasieni P, Barton A, Pitzalis C; STRAP collaborative group. Rivellese F, et al. Among authors: pitzalis c. Lancet Rheumatol. 2023 Nov;5(11):e648-e659. doi: 10.1016/S2665-9913(23)00241-2. Lancet Rheumatol. 2023. PMID: 38251532 Free article. Clinical Trial.
Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter--Determining Validation Requirements.
Humby F, Kelly S, Bugatti S, Manzo A, Filer A, Mahto A, Fonseca JE, Lauwerys B, D'Agostino MA, Naredo E, Lories R, Montecucco C, Tak PP, Fitzgerald O, Smith MD, Veale DJ, Choy EH, Strand V, Pitzalis C. Humby F, et al. Among authors: pitzalis c. J Rheumatol. 2016 Jan;43(1):208-13. doi: 10.3899/jrheum.141199. Epub 2015 Jun 1. J Rheumatol. 2016. PMID: 26034155 Review.
Stratified medicine in rheumatoid arthritis-the MATURA programme.
Barton A, Pitzalis C. Barton A, et al. Among authors: pitzalis c. Rheumatology (Oxford). 2017 Aug 1;56(8):1247-1250. doi: 10.1093/rheumatology/kew369. Rheumatology (Oxford). 2017. PMID: 28165532 Free PMC article. No abstract available.
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC).
Lliso-Ribera G, Humby F, Lewis M, Nerviani A, Mauro D, Rivellese F, Kelly S, Hands R, Bene F, Ramamoorthi N, Hackney JA, Cauli A, Choy EH, Filer A, Taylor PC, McInnes I, Townsend MJ, Pitzalis C. Lliso-Ribera G, et al. Among authors: pitzalis c. Ann Rheum Dis. 2019 Dec;78(12):1642-1652. doi: 10.1136/annrheumdis-2019-215751. Epub 2019 Oct 2. Ann Rheum Dis. 2019. PMID: 31582377 Free PMC article.
B Cell Synovitis and Clinical Phenotypes in Rheumatoid Arthritis: Relationship to Disease Stages and Drug Exposure.
Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC-R4RA Investigators. Rivellese F, et al. Among authors: pitzalis c. Arthritis Rheumatol. 2020 May;72(5):714-725. doi: 10.1002/art.41184. Epub 2020 Mar 17. Arthritis Rheumatol. 2020. PMID: 31785084 Free PMC article.
A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients.
Nerviani A, Di Cicco M, Mahto A, Lliso-Ribera G, Rivellese F, Thorborn G, Hands R, Bellan M, Mauro D, Boutet MA, Giorli G, Lewis M, Kelly S, Bombardieri M, Humby F, Pitzalis C. Nerviani A, et al. Among authors: pitzalis c. Front Immunol. 2020 May 5;11:845. doi: 10.3389/fimmu.2020.00845. eCollection 2020. Front Immunol. 2020. PMID: 32431716 Free PMC article.
354 results