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Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT).
Paton NI, Stöhr W, Arenas-Pinto A, Clarke A, Williams I, Johnson M, Orkin C, Chen F, Lee V, Winston A, Gompels M, Fox J, Sanders K, Dunn DT; Protease Inhibitor monotherapy Versus Ongoing Triple therapy (PIVOT) Trial Team. Paton NI, et al. EClinicalMedicine. 2024 Feb 10;69:102457. doi: 10.1016/j.eclinm.2024.102457. eCollection 2024 Mar. EClinicalMedicine. 2024. PMID: 38361989 Free PMC article.
A systematic analysis of the human immune response to Plasmodium vivax.
Bach FA, Muñoz Sandoval D, Mazurczyk M, Themistocleous Y, Rawlinson TA, Harding AC, Kemp A, Silk SE, Barrett JR, Edwards NJ, Ivens A, Rayner JC, Minassian AM, Napolitani G, Draper SJ, Spence PJ. Bach FA, et al. Among authors: spence pj. J Clin Invest. 2023 Oct 16;133(20):e152463. doi: 10.1172/JCI152463. J Clin Invest. 2023. PMID: 37616070 Free PMC article.
Alignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites.
Năstase AM, Barrett MP, Cárdenas WB, Cordeiro FB, Zambrano M, Andrade J, Chang J, Regato M, Carrillo E, Botana L, Moreno J, Regnault C, Milne K, Spence PJ, Rowe JA, Rogers S. Năstase AM, et al. Among authors: spence pj. PLoS Negl Trop Dis. 2023 Jul 24;17(7):e0011133. doi: 10.1371/journal.pntd.0011133. eCollection 2023 Jul. PLoS Negl Trop Dis. 2023. PMID: 37486920 Free PMC article.
Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: Safety and parasite growth dynamics.
Salkeld J, Themistocleous Y, Barrett JR, Mitton CH, Rawlinson TA, Payne RO, Hou MM, Khozoee B, Edwards NJ, Nielsen CM, Sandoval DM, Bach FA, Nahrendorf W, Ramon RL, Baker M, Ramos-Lopez F, Folegatti PM, Quinkert D, Ellis KJ, Poulton ID, Lawrie AM, Cho JS, Nugent FL, Spence PJ, Silk SE, Draper SJ, Minassian AM. Salkeld J, et al. Among authors: spence pj. Front Immunol. 2022 Aug 22;13:984323. doi: 10.3389/fimmu.2022.984323. eCollection 2022. Front Immunol. 2022. PMID: 36072606 Free PMC article. Clinical Trial.
In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel.
Murphy DJ, Dallal Bashi YH, McCoy CF, Boyd P, Brown L, Martin F, McMullen N, Kleinbeck K, Dangi B, Spence P, Hansraj B, Devlin B, Malcolm RK. Murphy DJ, et al. Among authors: spence p. Int J Pharm X. 2022 Jan 25;4:100112. doi: 10.1016/j.ijpx.2022.100112. eCollection 2022 Dec. Int J Pharm X. 2022. PMID: 35128382 Free PMC article.
Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel.
Dallal Bashi YH, Murphy DJ, McCoy CF, Boyd P, Brown L, Kihara M, Martin F, McMullen N, Kleinbeck K, Dangi B, Spence P, Hansraj B, Devlin B, Malcolm RK. Dallal Bashi YH, et al. Among authors: spence p. Int J Pharm X. 2021 Jul 14;3:100091. doi: 10.1016/j.ijpx.2021.100091. eCollection 2021 Dec. Int J Pharm X. 2021. PMID: 34977558 Free PMC article.
152 results