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Late-life voluntary wheel running reverses age-related aortic stiffness in mice: a translational model for studying mechanisms of exercise-mediated arterial de-stiffening.
Gioscia-Ryan RA, Clayton ZS, Fleenor BS, Eng JS, Johnson LC, Rossman MJ, Zigler MC, Evans TD, Seals DR. Gioscia-Ryan RA, et al. Among authors: zigler mc. Geroscience. 2021 Feb;43(1):423-432. doi: 10.1007/s11357-020-00212-1. Epub 2020 Jun 11. Geroscience. 2021. PMID: 32529594 Free PMC article.
Lifelong voluntary aerobic exercise prevents age- and Western diet- induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice.
Gioscia-Ryan RA, Clayton ZS, Zigler MC, Richey JJ, Cuevas LM, Rossman MJ, Battson ML, Ziemba BP, Hutton DA, VanDongen NS, Seals DR. Gioscia-Ryan RA, et al. Among authors: zigler mc. J Physiol. 2021 Feb;599(3):911-925. doi: 10.1113/JP280607. Epub 2020 Oct 28. J Physiol. 2021. PMID: 33103241 Free PMC article.
Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice.
Ballak DB, Brunt VE, Sapinsley ZJ, Ziemba BP, Richey JJ, Zigler MC, Johnson LC, Gioscia-Ryan RA, Culp-Hill R, Eisenmesser EZ, D'Alessandro A, Dinarello CA, Seals DR. Ballak DB, et al. Among authors: zigler mc. Aging Cell. 2020 Jan;19(1):e13074. doi: 10.1111/acel.13074. Epub 2019 Nov 21. Aging Cell. 2020. PMID: 31755162 Free PMC article.
Female C57BL/6N mice are a viable model of aortic aging in women.
Longtine AG, Venkatasubramanian R, Zigler MC, Lindquist AJ, Mahoney SA, Greenberg NT, VanDongen NS, Ludwig KR, Moreau KL, Seals DR, Clayton ZS. Longtine AG, et al. Among authors: zigler mc. Am J Physiol Heart Circ Physiol. 2023 Jun 1;324(6):H893-H904. doi: 10.1152/ajpheart.00120.2023. Epub 2023 Apr 28. Am J Physiol Heart Circ Physiol. 2023. PMID: 37115626
13 results