Wong PC - Search Results

1

A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD.

Irwin KE, Jasin P, Braunstein KE, Sinha IR, Garret MA, Bowden KD, Chang K, Troncoso JC, Moghekar A, Oh ES, Raitcheva D, Bartlett D, Miller T, Berry JD, Traynor BJ, Ling JP, Wong PC. Irwin KE, et al. Among authors: wong pc. Nat Med. 2024 Feb;30(2):382-393. doi: 10.1038/s41591-023-02788-5. Epub 2024 Jan 26. Nat Med. 2024. PMID: 38278991 Free PMC article.

2

Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.

Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. Chiang PM, et al. Among authors: wong pc. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16320-4. doi: 10.1073/pnas.1002176107. Epub 2010 Jul 26. Proc Natl Acad Sci U S A. 2010. PMID: 20660762 Free PMC article.

3

Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation.

Wu J, Petralia RS, Kurushima H, Patel H, Jung MY, Volk L, Chowdhury S, Shepherd JD, Dehoff M, Li Y, Kuhl D, Huganir RL, Price DL, Scannevin R, Troncoso JC, Wong PC, Worley PF. Wu J, et al. Among authors: wong pc. Cell. 2011 Oct 28;147(3):615-28. doi: 10.1016/j.cell.2011.09.036. Cell. 2011. PMID: 22036569 Free PMC article.

4

Rodent models of TDP-43: recent advances.

Tsao W, Jeong YH, Lin S, Ling J, Price DL, Chiang PM, Wong PC. Tsao W, et al. Among authors: wong pc. Brain Res. 2012 Jun 26;1462:26-39. doi: 10.1016/j.brainres.2012.04.031. Epub 2012 May 1. Brain Res. 2012. PMID: 22608070 Free PMC article. Review.

5

Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice.

LaClair KD, Manaye KF, Lee DL, Allard JS, Savonenko AV, Troncoso JC, Wong PC. LaClair KD, et al. Among authors: wong pc. Mol Neurodegener. 2013 Jun 13;8:18. doi: 10.1186/1750-1326-8-18. Mol Neurodegener. 2013. PMID: 23764200 Free PMC article.

6

Intraventricular Delivery of siRNA Nanoparticles to the Central Nervous System.

Shyam R, Ren Y, Lee J, Braunstein KE, Mao HQ, Wong PC. Shyam R, et al. Among authors: wong pc. Mol Ther Nucleic Acids. 2015 May 12;4:e242. doi: 10.1038/mtna.2015.15. Mol Ther Nucleic Acids. 2015. PMID: 25965552 Free article.

7

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.

Ling JP, Pletnikova O, Troncoso JC, Wong PC. Ling JP, et al. Among authors: wong pc. Science. 2015 Aug 7;349(6248):650-5. doi: 10.1126/science.aab0983. Science. 2015. PMID: 26250685 Free PMC article.

8

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.

Freibaum BD, Lu Y, Lopez-Gonzalez R, Kim NC, Almeida S, Lee KH, Badders N, Valentine M, Miller BL, Wong PC, Petrucelli L, Kim HJ, Gao FB, Taylor JP. Freibaum BD, et al. Among authors: wong pc. Nature. 2015 Sep 3;525(7567):129-33. doi: 10.1038/nature14974. Epub 2015 Aug 26. Nature. 2015. PMID: 26308899 Free PMC article.

9

The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model.

Li T, Braunstein KE, Zhang J, Lau A, Sibener L, Deeble C, Wong PC. Li T, et al. Among authors: wong pc. Nat Commun. 2016 Jul 4;7:12082. doi: 10.1038/ncomms12082. Nat Commun. 2016. PMID: 27373369 Free PMC article.

10

PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons.

Ling JP, Chhabra R, Merran JD, Schaughency PM, Wheelan SJ, Corden JL, Wong PC. Ling JP, et al. Among authors: wong pc. Cell Rep. 2016 Sep 27;17(1):104-113. doi: 10.1016/j.celrep.2016.08.071. Cell Rep. 2016. PMID: 27681424 Free PMC article.

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