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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b.
Uehara K, Lee WD, Stefkovich M, Biswas D, Santoleri D, Garcia Whitlock A, Quinn W 3rd, Coopersmith T, Creasy KT, Rader DJ, Sakamoto K, Rabinowitz JD, Titchenell PM. Uehara K, et al. Among authors: titchenell pm. J Clin Invest. 2024 Jan 30;134(7):e173782. doi: 10.1172/JCI173782. J Clin Invest. 2024. PMID: 38290087 Free PMC article.
Resolving the Paradox of Hepatic Insulin Resistance.
Santoleri D, Titchenell PM. Santoleri D, et al. Among authors: titchenell pm. Cell Mol Gastroenterol Hepatol. 2019;7(2):447-456. doi: 10.1016/j.jcmgh.2018.10.016. Epub 2018 Nov 3. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30739869 Free PMC article. Review.
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.
Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, Rabinowitz JD, Wellen KE. Zhao S, et al. Among authors: titchenell pm. Nature. 2020 Mar;579(7800):586-591. doi: 10.1038/s41586-020-2101-7. Epub 2020 Mar 18. Nature. 2020. PMID: 32214246 Free PMC article.
AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology.
Jaiswal N, Gavin M, Loro E, Sostre-Colón J, Roberson PA, Uehara K, Rivera-Fuentes N, Neinast M, Arany Z, Kimball SR, Khurana TS, Titchenell PM. Jaiswal N, et al. Among authors: titchenell pm. J Cachexia Sarcopenia Muscle. 2022 Feb;13(1):495-514. doi: 10.1002/jcsm.12846. Epub 2021 Nov 9. J Cachexia Sarcopenia Muscle. 2022. PMID: 34751006 Free PMC article.
37 results